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Displaying results 6981 - 6990 of 10000 in total
  1. Drug

    MaxAdFVIII

    go.drugbank.com/drugs/DB17713
    Experimental

    MaxAdFVIII is an adenoviral vector that expresses the full-length human Factor VIII (hFVIII) cDNA. First developed by GenStar, it is being investigated for the treatment of hemophilia.

  2. Drug

    Astegolimab

    go.drugbank.com/drugs/DB16386
    Investigational

    Astegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).

    Categories: Amino Acids, Peptides, and Proteins
  3. Drug

    NTLA-2001

    go.drugbank.com/drugs/DB18525
    Investigational

    NTLA-2001 is a clustered regularly interspaced short palindromic repeats CRISPR/ Cas9-based gene therapy consisting of a single guide RNA targeting the human TTR gene and a messenger RNA encoding Cas9.

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  4. Drug

    Dithioerythritol

    go.drugbank.com/drugs/DB01692
    Experimental

    A compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl

    Categories: Indicators and Reagents
  5. Drug

    Reposal

    go.drugbank.com/drugs/DB13805
    Experimental

    Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia.

    Categories: Hypnotics and Sedatives
  6. Drug

    Zunsemetinib

    go.drugbank.com/drugs/DB16502
    Investigational

    ATI-450 was under investigation in clinical trials (NCT05279417 and NCT05216224) for treating patients with rheumatoid arthritis and hidradenitis suppurativa, respectively. … Zunsemetinib is being investigated in a new clinical trial (NCT06374459) for the treatment of hormone receptor-positive and HER2-negative metastatic breast cancer with bone metastasis.

  7. Drug

    Candoxatrilat

    go.drugbank.com/drugs/DB11623
    Experimental

    A dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy

  8. Drug

    Zamubafusp alfa

    go.drugbank.com/drugs/DB32269
    Investigational

    Zamubafusp alfa is an immunoglobulin-peptide fusion protein.[L55038] It consists of a humanized IgG1 and p5R which is a pan-amyloid reactive peptide.[L55038]

  9. Drug

    Baloxavir

    go.drugbank.com/drugs/DB15675
    Investigational

    Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).

    Categories: Baloxavir and prodrugs
  10. Drug

    Ammonium lactate

    go.drugbank.com/drugs/DB06768
    Approved

    Ammonium lactate is the ammonium salt of lactic acid.