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Displaying results 6981 - 6990 of 8696 in total
  1. Drug

    Bevantolol

    go.drugbank.com/drugs/DB01295
    Investigational

    Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  2. Drug

    Sparfosic acid

    go.drugbank.com/drugs/DB03459
    Experimental

    These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom.

  3. Drug

    Hexobarbital

    go.drugbank.com/drugs/DB01355
    Experimental

    A barbiturate that is effective as a hypnotic and sedative.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  4. Target

    Tumor necrosis factor ligand superfamily member 11

    go.drugbank.com/bio_entities/BE0003517
    TargetHumans

    May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. … May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy (PubMed:22664871).

    Synonyms: Receptor activator of nuclear factor kappa-B ligand
  5. Target

    Hepatocyte nuclear factor 4-alpha

    go.drugbank.com/bio_entities/BE0004019
    TargetHumans

    Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922)...

    Synonyms: Nuclear receptor subfamily 2 group A member 1
  6. Drug

    Prostaglandin D2

    go.drugbank.com/drugs/DB02056
    Experimental

    Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.

  7. Drug

    ST-36

    go.drugbank.com/drugs/DB17275
    Experimental

    In 2017, it received orphan drug designation by the FDA for the treatment of glioma.[L47341]

  8. Drug

    Phelimin

    go.drugbank.com/drugs/DB18332
    Experimental

    [L48151] It is under investigation for the treatment of hyperphenylalaninemia.

  9. Drug

    OM85

    go.drugbank.com/drugs/DB16533
    Investigational

    OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.

  10. Drug

    P-BCMA-101

    go.drugbank.com/drugs/DB17371
    Investigational

    P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.