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Hydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalDue to these modifications, it presents a very high potency and comparable side effect profile to the parent compound.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: PALLADONE RETARD 4MG KAP, PALLADONE RETARD 8MG KAPCamphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnIt is used topically as a skin antipruritic and as an anti-infective agent. … [A254252,L43942] However, camphor can be found in several nonprescription medications at lower concentrations.[A254252]
Mixtures: Au Kah Chuen Skin Lotion, Kaz InhalantSynonyms: D-Camphor, Camphor(D)Etoposide
go.drugbank.com/drugs/DB00773ApprovedInvestigationalA semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair b...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 4-demethylepipodophyllotoxin β-D-ethylideneglucoside, 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-oneAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Mixtures: FROSDEM-PInternational brands: PK-MerzPropiverine
go.drugbank.com/drugs/DB12278ApprovedPropiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) . Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: MICTONORM UNO 30MG RET KAPNitroglycerin
go.drugbank.com/drugs/DB00727ApprovedInvestigationalNitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847. … [A180172] Nitroglycerin is used in a variety of different conditions, including angina pectoris due to coronary artery disease,[L7102,L7141,L38369,L42320] peri-operative hypertension, congestive heart
Products: NITROGLICERINA PH&T, Nitro-durOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur seems to have an antibacterial activity. It has been also used for acne.
Mixtures: Dr Lift BlemishProducts: Pharmassist Clarifex Ph Mud Crm 3.0%, MASCARILLA DE BARROKAI-1678
go.drugbank.com/drugs/DB16211InvestigationalKAI-1678 is under investigation in clinical trial NCT01106716 (Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia).
Benzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigationalBenzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
Mixtures: Kank-A, Blistex Kank-ACategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesGranisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: GRANI-DENK 1 MG/ ML- AMPOLLA DE 1 ML, GRANI DENK 1MG/ML KON