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Displaying results 61 - 70 of 10000 in total
  1. Drug

    Cilastatin

    go.drugbank.com/drugs/DB01597
    ApprovedInvestigational

    Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. … The first combination product containing both drugs was approved by the FDA in November of 1985 under the trade name Primaxin, marketed by Merck & Co.

    Mixtures: IMIPENEM E CILASTATINA SUN, IMIPENEM E CILASTATINA SUNProducts: IMCIL POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500MG/500MG PER VIAL
  2. Drug

    Benzoyl peroxide

    go.drugbank.com/drugs/DB09096
    ApprovedInvestigational

    [L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with [erythromycin],[L33264] [clindamycin],[L33269] or [adapalene]. … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover of epithelial cells.

    Mixtures: OXIMIN 10 MG/G + 50 MG/G JEL,50 G, OXIMIN 10 MG/G + 50 MG/G JEL,25 GProducts: Clinique Acne Solutions All-over Clearing Treatment, OXY COVER CREAM
  3. Drug

    Chlorine dioxide

    go.drugbank.com/drugs/DB12453
    Approved

    Chlorine Dioxide has been used in trials studying the treatment of Halitosis.

    Categories: Compounds used in a research, industrial, or household settingProducts: Pure O2 S, Pure O2-S F
  4. Drug

    Aluminum zirconium pentachlorohydrate

    go.drugbank.com/drugs/DB11147
    Approved

    Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.

    Products: On Duty 24 Hours Clear Protection Roll-On Anti-Perspirant Deodorant
  5. Drug

    Trabectedin

    go.drugbank.com/drugs/DB05109
    ApprovedInvestigational

    On October 23, 2015, the FDA approved trabectedin, (as Yondelis), for the treatment of specific soft tissue sarcomas. … Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair machinery.

    Products: TRABECTEDINA SUN, Trabectedin SUN 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  6. Drug

    SNS-314

    go.drugbank.com/drugs/DB06134
    Investigational

    SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. … SNS-314 inhibits tumor growth in a variety of preclinical models, and it is now being tested in single agent Phase 1 studies in patients with advanced solid tumours.

    Salts: SNS-314 mesylate
  7. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these agents over … [L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection.

    Products: TEMOZOLOMIDE SUN, Temozolomide Sun
  8. Drug

    Stearic acid

    go.drugbank.com/drugs/DB03193
    Approved

    Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.

    Mixtures: O Hui Veil Fit Dual Foundation 20, O Hui Veil Fit Dual Foundation 30Products: K Oxiderm Op, K Oxiderm OP Post Procedure skin care bruise
  9. Drug

    Technetium Tc-99m disofenin

    go.drugbank.com/drugs/DB09164
    ApprovedWithdrawn

    It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary … However disofenin is the most commonly used iminodiacetic acid since it has a high liver to renal extraction and its hepatic uptake is not as highly dependent on serum bilirubin levels (a competitive inhibitor

    Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingProducts: Kit for the Preparation of Technetium Tc99m Disofenin
  10. Drug

    1,2-icosapentoyl-sn-glycero-3-phosphoserine

    go.drugbank.com/drugs/DB14096
    Approved

    Salts: 1,2-icosapentoyl-sn-glycero-3-phosphoserine calciumSynonyms: 1,2-icosapentoyl-sn-glycero-3-phosphoserine