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Eribulin
go.drugbank.com/drugs/DB08871ApprovedInvestigationalEribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic
Categories: Heterocyclic Compounds, 1-RingProducts: ERIBULINA EG, HALAVEN 0.5 mg/ml solution for injectionZiprasidone
go.drugbank.com/drugs/DB00246ApprovedInvestigational[A190525] These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. … [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower incidence of metabolic adverse effects compared to other medications in the same class.[A190525]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: GEODON® CAPSULAS 80 MG, ZELDOX 20 MGIron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigationalIron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis
International brands: Ferosoft SMixtures: Marnatal F, Myferon 150 ForteMegestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approved17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. … As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Synonyms: MGA, 17α-Acetoxy-6-dehydro-6-methylprogesteroneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMethimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigationalin pregnancy due to a perceived lower risk of teratogenic effects. … Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.
Categories: Sex Hormones and Insulins, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: 1-Methylimidazole-2(3H)-thioneCilostazol
go.drugbank.com/drugs/DB01166ApprovedInvestigationalIt is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing calcium-induced contractions. … Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia
Synonyms: 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone, 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesGlyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigational[A183617] Glyburide was granted FDA approval on 1 May 1984.[L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120] … Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II.
Synonyms: 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea, 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylureaMixtures: GLUCOVANCE® 250/1.25 MG TABLETAS, DUPLAX 250 MG/1.25 MG FILM KAPLI TABLET, 30 ADETGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigationalGanirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. … [A252195] Ganirelix was first approved by the FDA on July 29, 1999.[L43070]
Categories: Sex Hormones and InsulinsProducts: NOVOLEX 0.25 MG/0.5 ML SOLUCIÓN INYECTABLE EN JERINGA PRECARGADA, ORGALUTRAN® 0.25 MG / 0.5 ML SOLUCION INYECTABLERoxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalIt works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. … [A245393] Roxadustat was first approved by the European Commission in August 2021.[L40323]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Ernevod 50 mg Film Kaplı Tablet (12 adet), EVRENZO 50 MG FİLM KAPLI TABLET, 12 ADETAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigational[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.
Synonyms: 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepineMixtures: NEUPAX DUO-S