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Tomligisiran
go.drugbank.com/drugs/DB19330InvestigationalTomligisiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis … B (CHB)).
Synonyms: RNA, ((1'-DE(6-AMINO-9H-PURIN-9-YL))DA-(5'->5')-CM-GM-CM-UM-GM-UM-AM-GM-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)A-UM-AM-AM-AM-UM-UM-GM-GM-UM-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN, -9-YL))DA), 3'-(O-(CIS-4-((3S,8S)-17-((2-(ACETYLAMICalcimycin
go.drugbank.com/drugs/DB19408InvestigationalPrimarily used as a biochemical tool for studying divalent cations in biological systems, Calcimycin also exhibits antibiotic activity against gram-positive bacteria and fungi. … Calcimycin is an ionophore and polyether antibiotic derived from Streptomyces chartreusensis.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingSynonyms: Antibiotic a-23187, 4-benzoxazolecarboxylic acid, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-Atisnolerbart
go.drugbank.com/drugs/DB19418InvestigationalAtisnolerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen
Synonyms: gamma4 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV1-8*03 (86.7%) -(IGHD) - IGHJ4*01 (93.3%), CDR-IMGT [8.8.13] (26-33.51- 58.97-109)) (1-120)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2, L92 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230),Mirtazapine Serotonin Antagonist Action Pathway
smpdb.ca/view/SMP0126817Drug actionMirtazapine is a strong antagonist of serotonin 5-HT2 and 5-HT3 receptors. … Mirtazapine is a potent histamine (H1) receptor antagonist, which may contribute to its powerful sedating effects.
Olea europaea pollen
go.drugbank.com/drugs/DB10378ApprovedOlea europaea pollen is the pollen of the Olea europaea plant. Olea europaea pollen is mainly used in allergenic testing.
Mixtures: Western 3 Tree Pollen Mix, Western 3 Tree Pollen MixSynonyms: Olea europaea pollen, european olive pollen extractMirtazapine H1-Antihistamine Action
smpdb.ca/view/SMP0062885Drug actionMirtazapine is a tetracyclic H1-antihistamine.
Mirtazapine Predicted Metabolism Pathway
smpdb.ca/view/SMP0174597MetabolicMetabolites of Mirtazapine are predicted with biotransformer.
XPro1595
go.drugbank.com/drugs/DB16454InvestigationalXPro1595 is an investigational dominant-negative protein that neutralizes soluble TNF.
Synonyms: SOLUBLE TUMOR NECROSIS FACTOR (1-METHIONINE,31-CYSTEINE,69-VALINE,87-HISTIDINE,101-ALANINE,145-ARGININE) (HUMAN CONSTRUCT XPRO1595), 31-THIOETHER WITH .ALPHA.-(3-((3-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL, HOMOSAPIENS TUMOR NECROSIS FACTOR,SOLUBLE FORM (V1>M, R31>C, C69>V, Y87>H, C101>A, A145>R), MONOMER, PEGYLATED ON CYSTEINE 31 : S-((3RS)-(2-((3-(.OMEGA.Mirtazapine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175072Drug actionMirtazapine is a first-generation ethanolamine H1-antihistamine.
Mirtazapine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145411Drug actionHistamine is transported into synaptic vesicles by a monoamine transporter then released into the synapse. … Mirtazapine inhibits the H1 histamine receptor, preventing the depolarization of the post-synaptic neuron.