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Tadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigational[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.
Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTAS, Finasteride and TadalafilCategories: Drugs Used in Erectile Dysfunction, Drugs Used in Benign Prostatic HypertrophyBivalirudin
go.drugbank.com/drugs/DB00006ApprovedInvestigationalBecause it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and blood pressure. … Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously.
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsProducts: ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML), Bivalirudin in 0.9% Sodium ChlorideChlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnUp to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites. … Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).
Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismSynonyms: N-(4-chlorophenylsulfonyl)-N'-propylurea, N-(p-chlorobenzenesulfonyl)-N'-propylureaVoriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigational[A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.[L34660] … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections.
Categories: Triazole and tetrazole derivatives, Metabolic Side Effects of Drugs and SubstancesProducts: VORICONAZOL ARISTO 100MG, VFEND 50MG TABLETCefadroxil
go.drugbank.com/drugs/DB01140ApprovedInvestigationalVet approvedWithdrawnLong-acting, broad-spectrum, water-soluble, cephalexin derivative.
Products: CEFADROXILO 500MG, GRUENCEF 500MG/5MLDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalDonepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. … [A182411] Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some cases, is used to manage
Mixtures: Memantine and Donepezil, Memantine and DonepezilCategories: donepezil and memantine, donepezil, memantine and Ginkgo foliumTioconazole
go.drugbank.com/drugs/DB01007ApprovedIn addition to being an antifungal, tioconazole also has antibacterial effects on certain Gram-positive cocci bacteria.[L50166] … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".
Mixtures: Gynecure Tandempk.vag Ov.300mg/vulv.crm1%w/w, Gynecure Tandempk.vag Ov.300mg/vulv.crm1%w/wCategories: Imidazole and Triazole Derivatives, Genito Urinary System and Sex HormonesVancomycin
go.drugbank.com/drugs/DB00512ApprovedInvestigationalSuch an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196]. … It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsProducts: Vancocin Cp Add-vantage Inj 500mg/vial, VANCOCINA CP 500MGPhylloquinone
go.drugbank.com/drugs/DB01022ApprovedInvestigational[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and X caused by deficiency or interference in the activity … [L33319] Phylloquinone has been synthesized since at least 1939,[A234384] and was approved by the FDA prior to 1955.[L33389]
Mixtures: Vitamin D2 and K1, NUTRILITE CHILDREN MULTIVITAMIN AND IRON CHEWABLE TABLETCategories: Diet, Food, and Nutrition, Blood and Blood Forming OrgansOrphenadrine
go.drugbank.com/drugs/DB01173ApprovedInvestigationalA muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Mixtures: Hovid Paracetamol and Orphenadrine Citrate Tablet 450mg/35mg, Orphenadrine Citrate, Aspirin and CaffeineCategories: Metabolic Side Effects of Drugs and Substances