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Hydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigationalHydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine]. … [L14312]** Hydroxychloroquine was granted FDA approval on 18 April 1955.[L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546]
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline, 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinolineGlioblastomas
go.drugbank.com/conditions/DBCOND0043840Synonyms: Glioblastoma, no ICD-O subtype, Glioblastoma, no International Classification of Diseases for Oncology subtypeSalmon calcitonin
go.drugbank.com/drugs/DB00017ApprovedInvestigationalSynthetic peptide, 32 residues long formulated as a nasal spray.
Products: Sandoz-calcitonin NS, MIACALCIC 100 IU AMPUL, 5 ADETSulfacetamide
go.drugbank.com/drugs/DB00634ApprovedAn anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Mixtures: Sodium Sulfacetamide and Sulfur Clarifying Wash in a Urea Vehicle, SulfaCleanse 8/4Synonyms: N(1)-Acetylsulfanilamide, N-((p-Aminophenyl)sulfonyl)acetamideMethylphenidate
go.drugbank.com/drugs/DB00422ApprovedInvestigationalBiphentin was designed to be an alternative to separate doses of immediate-release (IR) methylphenidate by providing a biphasic concentration-time profile when given as a single dose. … [A631] OROS is comprised of an osmotically active trilayer core surrounded by a semipermeable membrane with an immediate-release drug overcoat.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingSynonyms: methyl α-phenyl-α-(2-piperidyl)acetate, methyl α-phenyl-α-2-piperidinylacetateIodine
go.drugbank.com/drugs/DB05382ApprovedInvestigationalIodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. … Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Mixtures: O-Cal Prenatal Vitamin, O-Cal FA multivitaminSynonyms: I2Ketorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Mixtures: MAVIDOL K, Ixoba MCategories: Non COX-2 selective NSAIDS, Anti-Inflammatory Agents, Non-Steroidal (Non-Selective)Allyl-{4-[3-(4-Bromo-Phenyl)-Benzofuran-6-Yloxy]-but-2-Enyl}-Methyl-Amine
go.drugbank.com/drugs/DB03771ExperimentalFolic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedInadequate folate levels can result in a number of health concerns including cardiovascular disease, megaloblastic anemias, cognitive deficiencies, and neural tube defects (NTDs). … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is disrupted by anti-metabolite therapies such as [DB00563] as they function as DHFR inhibitors to prevent
Mixtures: Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA, O-Cal Prenatal VitaminCategories: Vitamin B Complex, Heterocyclic Compounds, 2-RingLeflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. … Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide