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Temsirolimus
go.drugbank.com/drugs/DB06287ApprovedInvestigationalTemsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Torisel Concentrate for Injection 25mg/mLImipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalImipramine may be used to treat depression and nocturnal enuresis in children [FDA Label]. … They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation.
International brands: Depsonil-PMCategories: Antidepressive Agents Indicated for Depression, Adrenergic alpha-1 Receptor AntagonistsMethylprednisolone hemisuccinate
go.drugbank.com/drugs/DB14644ApprovedInvestigationalA water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: MEDASON FOR INJECTION, Medixon Powder for Injection 500 mgUrokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawnUrokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase.
Products: Kinlytic (urokinase for Injection)Hydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigational[A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development of newer antihypertensive medications.
Categories: Antihypertensive Agents Indicated for Hypertension, Cytochrome P-450 CYP3A InhibitorsProducts: APRESOLINE FOR INJECTION 20 mg/ampoulePemtumomab
go.drugbank.com/drugs/DB18563ExperimentalPemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Synonyms: Murine MAb to polymorphic epithelial mucin, human milk fat globule 1Chlorhexidine
go.drugbank.com/drugs/DB00878ApprovedInvestigationalVet approvedWithdrawn[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses. … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.
Synonyms: 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)Mixtures: Softa-Man CHG Cutaneous Solution, Septi-sanQuinidine
go.drugbank.com/drugs/DB00908ApprovedThis alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.
Categories: Adrenergic alpha-1 Receptor Antagonists, P-glycoprotein inhibitorsProducts: Quinidine Gluconate for Inj 80mg/ml USPTyphoid Vi polysaccharide vaccine
go.drugbank.com/drugs/DB10803ApprovedInvestigationalIt is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older.
Categories: Antiinfectives for Systemic UseProducts: Typhim VI Solution for Injection in MultidoseMycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigational[A249175] This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. … [A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Mar-mycophenolic Acid