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Folic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedFolic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is disrupted by anti-metabolite therapies such as [DB00563] as they function as DHFR inhibitors to prevent
Synonyms: N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid, Vitamin B-9Mixtures: Genicin Vita-S, Kordel"s Kid"s Multivitamins Plus Lysine Chewable TabletBetula pendula tar oil
go.drugbank.com/drugs/DB11361ApprovedNutraceuticalThe origin plant, also known as the European white or silver birch, grows mainly in the northern hemisphere. … This oil is usually obtained by using both hydrodistillation and micro-distillation[A33154] and it is conformed mainly by [DB11143] and [DB11359].
Synonyms: European white birch tar oilAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. … Amlodipine is commonly used in the treatment of high blood pressure and angina.
Synonyms: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylateInternational brands: Amlodipine 5, Amlodipin-Mepha 5/10Tolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresolFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalIt works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone
Mixtures: Finasteride 0.1% / Minoxidil 7%, Finasteride 0.1% / Minoxidil 5%Categories: 5-alpha Reductase Inhibitors, Cytochrome P-450 SubstratesNorfloxacin
go.drugbank.com/drugs/DB01059ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Synonyms: 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäure, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acidCategories: 4-Quinolones, Heterocyclic Compounds, 2-RingSepantronium
go.drugbank.com/drugs/DB17062InvestigationalSepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and causes broad-range apoptosis.[A253167]
Synonyms: 1h-naphth(2,3-d)imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigationalValproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. … [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century.
Synonyms: 2-n-propyl-n-valeric acid, n-DPAMixtures: Depakine Chronosphere 50 mg Retardgranulat in Beuteln, Depakine Chronosphere 50 mg Retardgranulat in BeutelnMiconazole
go.drugbank.com/drugs/DB01110ApprovedVet approvedMiconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. … [A214523, L14021] It is currently available as a variety of prescription and over the counter products.
Synonyms: 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole, 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazoleInternational brands: Femizol-MGlycerin
go.drugbank.com/drugs/DB09462ApprovedInvestigationalA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Mixtures: Mycellcare iT s, MINICA S ENEMACategories: Cytochrome P-450 CYP2E1 Inducers, Cytochrome P-450 Enzyme Inducers