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Human immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders. … IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population.
Products: PRIVIGEN® 10% (2.5 G/25ML), BLAUIMUNO® 50MG/MLPhenolphthalein
go.drugbank.com/drugs/DB04824ApprovedWithdrawnPhenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.
Mixtures: EX-lax Light Formula Lax W Stool Soften TabProducts: EX-lax Chocolated Tab 95mg, Alophen Tab 60mgPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalPaliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug. … It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism.
Products: INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 ml, INVEGA SUSTENNA® SUSPENSIÓN DE LIBERACIÓN PROLONGADA DE 25MGProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedProgesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy. … Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label].
Synonyms: (S)-Pregn-4-en-3,20-dioneProducts: PMS-progesterone Inj 50mg/ml USP, CYCLOGEST 400MG PESSARIESPalbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigational[L5867] It was originally FDA approved on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and its indications were updated in April 2019 to include male … [A176810] Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as key regulators of cell growth.
Products: PMS-palbociclib, Ibrance Capsules 100mgRofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnRofecoxib has a half-life of 17 hours and its mean oral bioavailability at therapeutically recommended doses of 125, 25, and 50 mg is approximately 93%. … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras.
Products: DIEX 50MG TABLETAS, Vioxx Tab 25mgFlavoxate
go.drugbank.com/drugs/DB01148ApprovedIt may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem] … A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear.
Products: UROXATE TABLET 100MG, PMS-flavoxatePrimidone
go.drugbank.com/drugs/DB00794ApprovedVet approvedPrimidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. … [L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112]
Products: Mysoline Tab 250mg, Mysoline 250mg TabAmphetamine
go.drugbank.com/drugs/DB00182ApprovedIllicitInvestigationalIt was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. … Amphetamine structure presents one chiral center and it exists in the form of dextro- and levo-isomers.[A18540] The first product of Smith, Kline and French was approved by the FDA on 1976.
Mixtures: Dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, amphetamine sulfate ER, Dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, amphetamine sulfate ERProducts: Adzenys ER, PMS-amphetamines XRDoxylamine
go.drugbank.com/drugs/DB00366ApprovedInvestigationalVet approvedIt is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Mixtures: DICLECTIN DELAYED RELEASE TABLETS 10MG/10MG, BONJESTA® XR 20MGProducts: SLEEP AID 25mg, SCHLAF TABS RATIO 25MG TAB