Search
Dostarlimab
go.drugbank.com/drugs/DB15627ApprovedInvestigationalA prospective phase II study in patients with mismatch repair-deficient locally advanced rectal cancer resulted in all twelve patients exhibiting a complete clinical response.[A248905] … [L33340] A companion diagnostic device - the VENTANA MMR RxDx Panel - was also approved alongside this indication to select appropriate patients for treatment.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsPeginterferon alfa-2b
go.drugbank.com/drugs/DB00022ApprovedInvestigationalPeginterferon alfa-2b is available as a variable dose injectable product (tradename Pegintron) used for the treatment of chronic Hepatitis C. … Peginterferon alfa-2b was used alongside [DB00811] with the intent to cure, or achieve a sustained virologic response (SVR), after 48 weeks of therapy.
Categories: Compounds used in a research, industrial, or household settingAlanine
go.drugbank.com/drugs/DB00160ApprovedInvestigationalNutraceuticalAlanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination.
Mixtures: AA-Ven, Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose InjecSynonyms: L-Alanin, L-alanineProline
go.drugbank.com/drugs/DB00172ApprovedInvestigationalNutraceuticalProline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond. … Proline is a non-essential amino acid that is synthesized from glutamic acid. It is an essential component of collagen and is important for proper functioning of joints and tendons.
Mixtures: AA-Ven, Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose InjecSynonyms: L-Prolin, L-ProlinaPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429].
Mixtures: Pomada De La Campana Triple Antibiotic Pain Relief, Tribioticlc Lc LcPariglasgene brecaparvovec
go.drugbank.com/drugs/DB16801Approved[L64050,L64051] It is administered as a single, one-time intravenous infusion. … Pariglasgene brecaparvovec-opnr is an adeno-associated virus serotype 8 (AAV8)–based gene therapy for glycogen storage disease type Ia (GSDIa), a disorder caused by deficiency of the enzyme glucose-6-phosphatase
Camphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnCamphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. It is used topically as a skin antipruritic and as an anti-infective agent. … When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity.
Mixtures: Swan Brand Qian Li Zui Fong Yew Liniment, HAI-O QIAN LI ZHUI FENG YOU LINIMENTProducts: Formula AIomeprol
go.drugbank.com/drugs/DB11705ApprovedInvestigationalIomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use.
Categories: Compounds used in a research, industrial, or household settingMiltefosine
go.drugbank.com/drugs/DB09031ApprovedInvestigationalThe CDC has also recommended it as a first line treatment for free-living amebae (FLA) infections such as primary amebic meningoencephalitis and granulomatous amebic encephalitis. … Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent.
Leucine
go.drugbank.com/drugs/DB00149ApprovedInvestigationalNutraceuticalAn essential branched-chain amino acid important for hemoglobin formation.
Salts: L-Leucine hydrochlorideMixtures: Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec, Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec