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Displaying results 7151 - 7160 of 10000 in total
  1. Pathway

    Cardiolipin Biosynthesis CL(20:3(11Z,14Z,17Z)/20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/20:2(11Z,14Z))

    smpdb.ca/view/SMP0250427
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
  2. Drug

    Mezagitamab

    go.drugbank.com/drugs/DB16370
    Investigational

    Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and Efficacy of TAK-079 in Participants With Persistent/chronic Primary Immune Thrombocytopenia).

    Synonyms: (1-453) (HOMO SAPIENS VH (IGHV3-23*01 (89%) (IGHD)-I, IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1 (2'-PHOSPHO-ADP-RIBOSYL CYCLASE, ANTIGENE CD38))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN HUMANIZED
  3. Drug

    Yohimbine

    go.drugbank.com/drugs/DB01392
    ApprovedInvestigationalVet approvedWithdrawn

    A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.

    Categories: Heterocyclic Compounds, 2-Ring, Adrenergic alpha-2 Receptor AntagonistsInternational brands: Baron-X
  4. Drug

    Capsicum

    go.drugbank.com/drugs/DB10897
    Approved

    Capsicum (Chili pepper) allergenic extract is used in allergenic testing.

    Mixtures: Cbd-kings With Lidocaine 4%, Odynia-UProducts: ABC Lokale Schmerz‐Therapie Aktiv‐Pflaster 4,8 mg wirkstoffhaltiges Pflaster
  5. Drug

    Papain

    go.drugbank.com/drugs/DB11193
    ApprovedWithdrawn

    Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, _Carica papaya_ and _Vasconcellea cundinamarcensis_. … Present in over-the-counter mixture products consisting of different digestive enzymes, its active site contains a catalytic diad that plays a role in breaking peptide bonds.

    Mixtures: Master Key Formula 3 Tab, NATURE'S BOUNTY NATUREL B-COMPLEX AND B-12 TABLET, 90 ADETProducts: Papaya Enzyme - Tablet 30 mg, PRODEGEL ®
  6. Target

    Interleukin-3

    go.drugbank.com/bio_entities/BE0000125
    TargetHumans

    Cytokine secreted predominantly by activated T-lymphocytes as well as mast cells and osteoblastic cells that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed:2556442). Al...

    Polypeptides: Interleukin-3Synonyms: IL-3
  7. Target

    Galectin-3

    go.drugbank.com/bio_entities/BE0001353
    TargetHumans

    May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration.

    Polypeptides: Galectin-3Synonyms: Mac-2 antigen, Gal-3
  8. Target

    Lipase 3

    go.drugbank.com/bio_entities/BE0001503
    TargetEnzymeYeast

    Polypeptides: Lipase 3
  9. Target

    Stromelysin-3

    go.drugbank.com/bio_entities/BE0003691
    TargetHumans

    May play an important role in the progression of epithelial malignancies

    Polypeptides: Stromelysin-3Synonyms: SL-3
  10. Target

    Cytohesin-3

    go.drugbank.com/bio_entities/BE0004433
    TargetHumans

    Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity)

    Polypeptides: Cytohesin-3Synonyms: ARF nucleotide-binding site opener 3, PH, SEC7 and coiled-coil domain-containing protein 3