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Fasinumab
go.drugbank.com/drugs/DB12157InvestigationalFasinumab is a human IgG1k monoclonal antibody targeted against nerve growth factor (NGF). … [A241190] It has since been recognized for its role in nociceptive signaling transduction and has thus become an attractive target in the treatment of chronic pain conditions.
Pirlindole
go.drugbank.com/drugs/DB09244ExperimentalThis drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia. … Pirlindole is a selective, reversible inhibitor of monoamine oxidase (MAO) subtype A (MAO-A) that is approved in several European and non-European countries for the treatment of major depression.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesMultipotent adult arogenitor cells
go.drugbank.com/drugs/DB15742InvestigationalThe cells for creation of the product are isolated from a qualified donor and expanded on a large scale and then frozen until use. After administration, the cells are cleared from the body over time. … MultiStem is an intravenously-administered, off-the-shelf proprietary product developed which comprises Multipotent Adult Progenitor Cells (MAPCs).
Washed Microbiota Transplantation
go.drugbank.com/drugs/DB15745InvestigationalWashed microbiota preparation (WMT) involves a method wherein FMT is used, but the preparation undergoes microfiltration through an automatic purification system combined with repeated centrifugation and … Fecal microbiota transplantation (FMT) is effective in enhancing the gut microbiota of patients experiencing a high range of disease states, including Clostridioides difficile (C. diff) infection, Crohn
Galantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigational[L13571] It is therefore not considered to be a disease-modifying drug. … Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease
Products: GALANTAMIN 1A PHAR16MG HAR, GALANTAMIN 1A PHAR24MG HARDaclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnDaclizumab is a composite of human (90%) and murine (10%) antibody sequences. … The murine sequences were derived from the complementarity-determining regions of a murine anti-Tac antibody.
Amitraz
go.drugbank.com/drugs/DB11373ExperimentalVet approvedAmitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. … Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-(methyliminodimethylidyne)bis-2,4-xylidineMM-093
go.drugbank.com/drugs/DB05512InvestigationalMM-093 is a recombinant version of human alpha-fetoprotein (hAFP), an immunomodulatory serum protein normally produced at very high levels by the fetus and present in low levels in the blood of adults … Research on AFP suggests that it may play a role in modulating the immune system of the mother in order to protect the developing fetus during pregnancy.
Perospirone
go.drugbank.com/drugs/DB08922InvestigationalIt also displays affinity towards 5HT1A receptors as a partial agonist. … It is also shown to be less associated with extrapyramidal symptoms as a side effect compared to [DB00502].
Synonyms: cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximideVanoxerine
go.drugbank.com/drugs/DB03701InvestigationalVanoxerine is a highly selective dopamine transporter antagonist. It was synthesized in the late 1970s and developed as a potential treatment for depression. … [A19824] Vanoxerine was later evaluated as a potential treatment for cocaine addiction due to its ability to block dopamine reuptake with a slower dissociation rate than cocaine.