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Fovinaciclib
go.drugbank.com/drugs/DB21721InvestigationalThe usage of the INN stem '-ciclib' in the name indicates that Fovinaciclib is a cyclin dependant kinase inhibitor. Fovinaciclib has a monoisotopic molecular weight of 548.3 Da.
Zeprumetostat
go.drugbank.com/drugs/DB21740InvestigationalThe usage of the INN stem '-metostat' in the name indicates that Zeprumetostat is a histone N-methyltransferase inhibitor. Zeprumetostat has a monoisotopic molecular weight of 548.34 Da.
Seproxetine
go.drugbank.com/drugs/DB06731ExperimentalIt is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an antidepressant but development was never completed and the drug was never marketed.
R-851
go.drugbank.com/drugs/DB05747ExperimentalR-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate the human body's immnune system to attack virus-infected cells and tumor cells. … It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus (HPV), the sexually transmitted virus that causes most cases of cervical cancer.
N,N-dimethylarginine
go.drugbank.com/drugs/DB01686ExperimentalIt is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health.
Synonyms: L-NG,NG-dimethylarginine, N(G),N(G)-Dimethylarginine3'-phospho-5'-adenylyl sulfate
go.drugbank.com/drugs/DB02902Experimental3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate … This compound also is an important step in the process of sulfur fixation in plants and microorganisms.
JNJ-55308942
go.drugbank.com/drugs/DB19110InvestigationalJNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).
Ianalumab
go.drugbank.com/drugs/DB16666InvestigationalIanalumab is under investigation in clinical trial NCT01930175 (Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris).
DSP107
go.drugbank.com/drugs/DB17501InvestigationalDSP107 is a bi-functional, trimeric, fusion protein composed of sequences from the extracellular domain of SIRPα and 4-1BBL.