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Interferon Kappa
go.drugbank.com/drugs/DB15749Experimentala 27-amino acid signal peptide conserved in type I interferons. … This gene encoding for this interferon is expressed in human epidermal keratinocytes.
Ulotaront
go.drugbank.com/drugs/DB15665InvestigationalSEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. … [L12891] An initial clinical study has shown this drug may be effective against both positive and negative symptoms of schizophrenia.
Avasopasem manganese
go.drugbank.com/drugs/DB16354Investigational[L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19. … Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.
Troleandomycin
go.drugbank.com/drugs/DB13179ApprovedA macrolide antibiotic that is similar to erythromycin.
Dimethylcurcumin
go.drugbank.com/drugs/DB06133InvestigationalDimethylcurcumin is a synthetic chemical compound that is loosely based on a compound found in curcumin. It is a novel anti-androgen that enhances androgen receptor degradation.
XP12B
go.drugbank.com/drugs/DB04928InvestigationalXP12B is being developed by Xanodyne Pharmaceuticals for the treatment of menorrhagia (heavy menstrual bleeding). It was granted Fast Track status for this indication by the FDA in November 2004.
Anti-SARS-CoV-2 REGN-COV2
go.drugbank.com/drugs/DB15691InvestigationalThis drug is a combination of the antibodies REGN10933 and REGN10987, derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. … trial will study the effects of this drug on hospitalized COVID-19 patients, symptomatic COVID-19 patients (non-hospitalized), and uninfected individuals at high-risk of infection, including contacts of an
HY10275
go.drugbank.com/drugs/DB05079ExperimentalHY10275 is a novel compound specifically designed to modulate two key neurobiological mechanisms that interfere with the sleeping process. … HY10275 is highly selective for histamine H1 and serotonin 5HT2a, two chemical receptors that are known to impact the ability to fall asleep and stay asleep.
1alpha,24S-Dihydroxyvitamin D2
go.drugbank.com/drugs/DB06117ExperimentalLR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. … It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol, but much lower toxicity.