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Endoglucanase A
go.drugbank.com/bio_entities/BE0002017TargetClostridium thermocellumThis enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
Polypeptides: Endoglucanase ASynonyms: Cellulase AArylsulfatase A
go.drugbank.com/bio_entities/BE0003195TargetEnzymeHumansLysosomal enzyme that catalyzes the hydrolysis of cerebroside-3-sulfate (N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine) into cerebroside and sulfate, a reaction that requires the activator protein
Polypeptides: Arylsulfatase ABontoxilysin-A
go.drugbank.com/bio_entities/BE0004102TargetClostridium botulinumPolypeptides: Bontoxilysin-ASynonyms: A, boNT/AFilamin-A
go.drugbank.com/bio_entities/BE0009099TargetHumansPlays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity … Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins.
Polypeptides: Filamin-ASynonyms: FLN-AToxin A
go.drugbank.com/bio_entities/BE0010938TargetPeptoclostridium difficileToxin A Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis … Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains
Polypeptides: Toxin ASevere Hemophilia A
go.drugbank.com/conditions/DBCOND0034640Drugs: Valoctocogene roxaparvovecSynonyms: Hemophilia A, Severe, Severe Haemophilia AAcacia
go.drugbank.com/drugs/DB10451ApprovedAcacia allergenic extract is used in allergenic testing.
Synonyms: Kher resin, Acacia cufodontii resinMyrrh
go.drugbank.com/drugs/DB11605ApprovedInvestigationalExtractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, obtained from Commiphora
Mixtures: LA FEMME V Feminine CleanserSynonyms: Bola resin, Commiphora molmol resinSurovatamig
go.drugbank.com/drugs/DB19420InvestigationalTNB-486 is under investigation in clinical trial NCT06564038 (A Study of AZD0486 Monotherapy or in Combination With Other Anti-cancer Agents for Mature B-cell Malignancies).
Synonyms: a) CH2 L92, G4v5 h P10, G4v4 CH2 A1.3, A1.2, G4v32 CH, H-gamma4 heavy chain anti-CD3D/CD3E dimer, Homo sapiens (1-450) [VH (Homo sapiens IGHV3-9*01 (100%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123)-Homo sapiens IGHG4*01 nG4m(