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Afegostat
go.drugbank.com/drugs/DB04545InvestigationalSynonyms: (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diolCategories: Heterocyclic Compounds, 1-RingNiflumic acid
go.drugbank.com/drugs/DB04552InvestigationalNiflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
Categories: Heterocyclic Compounds, 1-Ring, Selective Cyclooxygenase 2 Inhibitors (NSAIDs)Latamoxef
go.drugbank.com/drugs/DB04570ApprovedLatamoxef is a broad- spectrum beta-lactam antibiotic similar in structure to the cephalosporins except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain cephalosporins
Categories: Heterocyclic Compounds, 2-RingThiotepa
go.drugbank.com/drugs/DB04572ApprovedInvestigationalIt is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. … N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: N,N′,N′′-tri-1,2-ethanediyl-, Phosphorothioic triamide, N,N′,N′′-tri-1,2-ethanediyl-Cycloleucine
go.drugbank.com/drugs/DB04620ExperimentalIt is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments.
Synonyms: 1-amino-1-cyclopentanecarboxylic acid, 1-aminocyclopentane-1-carboxylic acidApramycin
go.drugbank.com/drugs/DB04626InvestigationalVet approvedApramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans. … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.
Synonyms: 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamine, 4-O-(3α-amino-6α-((4-amino-4-deoxy-α-D-glucopyranosyl)oxy)-2,3,4,5aβ,6,7,8,8aα-octahydro-8β-hydroxy-7β-(methylamino)pyrano(3,2-b)pyran-2α-yl)-2-deoxy-D-streptamineProducts: TP-APRA 500 WSP ApramycinSulphate 500mg/g Water Soluble PowderCholine alfoscerate
go.drugbank.com/drugs/DB04660InvestigationalA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids.
Synonyms: sn-3-GPC, glycerol-3-phosphocholineProducts: MEDOTİLİN 1000 MG/ 4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 3 ADETCamptothecin
go.drugbank.com/drugs/DB04690InvestigationalCamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, <i>Camptotheca acuminata</i>. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I.
Categories: P-glycoprotein substrates, Topoisomerase I InhibitorsSynonyms: D-camptothecin, 20(S)-camptothecinegamma-Butyrolactone
go.drugbank.com/drugs/DB04699ExperimentalIllicitIt is also used as a pharmacological agent and solvent. … One of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate.
Categories: 4-Butyrolactone, Heterocyclic Compounds, 1-RingSynonyms: 4-butyrolactone, γ-butyrolactoneCitraconic acid
go.drugbank.com/drugs/DB04734ExperimentalCitraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Synonyms: (Z)-2-Methyl-2-butenedioic acid, 2-Methyl-2-butenedioic acid