Latamoxef is a broad- spectrum beta-lactam antibiotic similar in structure to the cephalosporins except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain cephalosporins. It has... It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
- Mechanism
- Curator reviewed
Penicillins acylate the penicillin-sensitive transpeptidase C-terminal domain (the penicillin-binding protein) by opening the lactam ring. This inactivation of the enzyme prevents the formation of a cross-link of two linear peptidoglycan strands, inhibiting the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that amoxicllin interferes with an autolysin inhibitor.
- Primary indication
- Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins.Curator reviewed
- Formula / weight
- C20H20N6O9S · 520.473 g/mol (avg)
- Also known as
- Festamoxin · Lamoxactam · Moxalactam
Resolves to
JWCSIUVGFCSJCK-CAVRMKNVSA-NSMILES[H][C@]12OCC(CSC3=NN=NN3C)=C(N1C(=O)[C@]2(NC(=O)C(C(O)=O)C1=CC=C(O)C=C1)OC)C(O)=OWhat you can answer from here — as of September 12, 2026
Which drugs share a target with Latamoxef, and which of those have an active Phase 3 trial?
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