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Calcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalIn addition to promoting fatty acid synthesis and inhibiting lipolysis, calcitriol has been demonstrated to increase energy efficiency by suppressing UCP2 expression, which is modulated by signaling pathways … It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to [DB00169] (vitamin D3) in the skin, which is then converted
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 1-alpha-25-Dihydroxyvitamin D3Ipratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigational[A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved in 1986, while the combination product of ipratropium and [albuterol … Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent.
Mixtures: BERODUAL N METERED DOSE INHALER, BERODUAL N METERED DOSE INHALERCategories: Agents to Treat Airway DiseaseTerbinafine
go.drugbank.com/drugs/DB00857ApprovedInvestigationalVet approved[A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall … Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.
Mixtures: Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%, Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersPhenoxymethylpenicillin
go.drugbank.com/drugs/DB00417ApprovedInvestigationalVet approvedAn orally active naturally penicillin, phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by penicillin G-sensitive microorganisms … While there have been no controlled clinical efficacy studies that were conducted, phenoxymethylpenicillin has been suggested by the American Heart Association and the American Dental Association for use
Categories: Penicillin G, Heterocyclic Compounds, 1-RingSynonyms: (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedEtodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. … Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Mixtures: NuDroxiPAK E-400, ETOTIO 400 MG/8 MG FILM TABLET, 20 ADETCategories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticHypophosphatemia, Familial
go.drugbank.com/conditions/DBCOND0036228Synonyms: HPDR I - Hypophosphatemic vitamin D-resistant rickets, HPDR I - Hypophosphataemic vitamin D-resistant ricketsAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. … Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), an important vasodilator that decreases blood pressure [A175321].
Synonyms: 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylateInternational brands: Amlodipine 5, Amlodipin-Mepha 5/10Prednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approvedPrednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. … [A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Synonyms: Predniso(lo)ne, delta(1)-HydrocortisoneInternational brands: Ak-Pred, Di-Adreson FLimaprost
go.drugbank.com/drugs/DB09211InvestigationalProstaglandins have a wide variety of actions, including, but not limited to muscular constriction and mediation of inflammation. … Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog.
Categories: Prostaglandins EProducts: OPALMON TABLETS 5 ugMalignant Melanoma
go.drugbank.com/conditions/DBCOND0029825Synonyms: Malignant melanoma, no ICD-O subtype, Malignant melanoma, no International Classification of Diseases for Oncology subtype