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Pyridoxine
go.drugbank.com/drugs/DB00165ApprovedInvestigationalNutraceuticalVet approvedPyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s mechanism of action which competitively inhibits … Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods.
Mixtures: Betex SC Tablet, Genicin Vita-SCategories: Vitamin B Complex, Heterocyclic Compounds, 1-RingCapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements … Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations.
Synonyms: (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-8-Methyl-N-vanillyl-6-nonenamideMixtures: s Cream, Better Nature Pain Relief CreamHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigationalHydroxyzine is a first-generation histamine H<sub>1</sub>-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.
Mixtures: DOLMARAL®Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSickle Cell Crisis
go.drugbank.com/conditions/DBCOND0051870Drugs: HydroxyureaSynonyms: Hemoglobin S disease with crisis (disorder)Canagliflozin
go.drugbank.com/drugs/DB08907ApprovedInvestigationalCanagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise … 2 diabetes mellitus [L5897], [FDA label].
Mixtures: Vokanamet (Canagliflozin 150mg/ Metformin 500mg) Film-Coated Tablet, Vokanamet (Canagliflozin 150mg/ Metformin 850mg) Film-Coated TabletCategories: metformin and canagliflozin, Cytochrome P-450 SubstratesAmbroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalAmbroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. … The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important
Mixtures: ULAX-C, BROGAL TCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalTranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. … It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent.
Synonyms: trans-4-aminomethylcyclohexane-1-carboxylic acid, trans-4-(Aminomethyl)cyclohexanecarboxylic acidInternational brands: Cyclo-FGlimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalIt is sometimes classified as a third-generation SU because it has larger substitutions than other second-generation SUs. … Compared to [glipizide], another second SU drug, glimepiride has a longer duration of action.
Mixtures: ILET B GLIMEPIRIDA + METFORMINA CLORHIDRATO 2 MG+500 MG TABLETAS DE LIBERACION PROLONGADA, AMARYL® M SRCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesBortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigationalBortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. … [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid, N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideInflammatory Muscle Disease
go.drugbank.com/conditions/DBCOND0155571Drugs: Acetaminophen · Acetylsalicylic acid · Azapropazone · Diazepam · Diclofenac · Methyl salicylate +2 moreSynonyms: Inflammation;Muscle(S)