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Retinol-binding protein 4
go.drugbank.com/bio_entities/BE0000314CarrierTargetHumansRetinol-binding protein that mediates retinol transport in blood plasma (PubMed:5541771). Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates ...
Polypeptides: Retinol-binding protein 4Fibroblast growth factor 4
go.drugbank.com/bio_entities/BE0000326TargetHumansPlays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. May play a role in embryonic molar tooth bud d...
Polypeptides: Fibroblast growth factor 4Synonyms: FGF-4, HBGF-4Metabotropic glutamate receptor 4
go.drugbank.com/bio_entities/BE0000833TargetHumansG protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits ad...
Polypeptides: Metabotropic glutamate receptor 4Leukotriene A-4 hydrolase
go.drugbank.com/bio_entities/BE0001680TargetHumansBifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities. Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the pro-inflammatory mediator leukotriene B4 (LTB4) (PubMed:1191...
Polypeptides: Leukotriene A-4 hydrolaseSynonyms: LTA-4 hydrolase, Leukotriene A(4) hydrolaseUDP-glucose 4-epimerase
go.drugbank.com/bio_entities/BE0001901TargetEnzymeEscherichia coli (strain K12)Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. It is only active on UDP-galactose and UDP-glucose.
Polypeptides: UDP-glucose 4-epimeraseSynonyms: UDP-galactose 4-epimerasedTDP-4-dehydrorhamnose reductase
go.drugbank.com/bio_entities/BE0001971TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. RmlD uses NADH and NADPH nearly equally well.
Polypeptides: dTDP-4-dehydrorhamnose reductaseSynonyms: dTDP-4-keto-L-rhamnose reductase, dTDP-6-deoxy-L-lyxo-4-hexulose reductase4-hydroxy-tetrahydrodipicolinate reductase
go.drugbank.com/bio_entities/BE0001986TargetEscherichia coli (strain K12)Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. Can use both NADH and NADPH as a reductant, with NADH being twice as effective as NADPH.
Polypeptides: 4-hydroxy-tetrahydrodipicolinate reductaseFunction: 4-hydroxy-tetrahydrodipicolinate reductaseBeta-1,4-galactosyltransferase 4
go.drugbank.com/bio_entities/BE0002263TargetHumans[->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer (PubMed:17690104). … Transfers Gal residue via a beta1->4 linkage to terminal 6-O-sulfoGlcNAc within the LacNac unit of core 2 O-glycans forming 6-sulfo-sialyl-Lewis X (sLex).
Polypeptides: Beta-1,4-galactosyltransferase 4Synonyms: Beta-1,4-GalTase 4, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 44-chlorobenzoyl CoA dehalogenase
go.drugbank.com/bio_entities/BE0002495TargetPseudomonas sp. DJ-12Polypeptides: 4-chlorobenzoyl CoA dehalogenase4'-phosphopantetheinyl transferase sfp
go.drugbank.com/bio_entities/BE0002687TargetBacillus subtilis (strain 168)Activates the seven peptidyl carrier protein (PCP) domains of the first three subunits (SrfAA, SrfAB and SrfAC) of surfactin synthetase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (
Polypeptides: 4'-phosphopantetheinyl transferase sfp