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Bivalirudin
go.drugbank.com/drugs/DB00006ApprovedInvestigationalBivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. … Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously.
Products: OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 10 ADET, OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 1 ADETEmpagliflozin
go.drugbank.com/drugs/DB09038ApprovedInvestigationalEmpagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. … [A203453] It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus.
Synonyms: 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene, (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitolMixtures: GLYXAMBI® 10 MG/ 5 MG, GLYXAMBI® 10 MG/ 5 MGValdecoxib
go.drugbank.com/drugs/DB00580ApprovedWithdrawnValdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Categories: Heterocyclic Compounds, 1-Ring, COX-2 InhibitorsProducts: BEXTRA ® 10 MG TABLETAS RECUBIERTAS, BEXTRA®20 MG TABLETAS RECUBIERTASVoriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigational[A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.[L34660] … The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [fluconazole]-resistant organisms.
Synonyms: (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanolCategories: 14-alpha Demethylase Inhibitors, Heterocyclic Compounds, 1-RingOfatumumab
go.drugbank.com/drugs/DB06650ApprovedInvestigational[L12753] The FDA subsequently approved ofatumumab for the treatment of RMS on August 20, 2020. … [L12612] Although it has a similar molecular mechanism of action as [rituximab], another CD-20 monoclonal antibody used in the treatment of rheumatoid arthritis and B-cell non-Hodgkin's lymphoma, ofatumumab
Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: Jemvy 20 mg/0,4 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET, JEMVY 20 MG/0,4 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETCenobamate
go.drugbank.com/drugs/DB06119ApprovedInvestigational[L10653] Cenobamate was granted FDA approval on 21 November 2019.[L10653] … Cenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures.
Categories: Heterocyclic Compounds, 1-RingProducts: XCOPRI TITRATION PACK 50 mg, 100 mg, XCOPRI TITRATION PACK 150 mg, 200 mgDexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalin the epithelium[A32373]. … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.
Synonyms: D-panthenol 50, (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamideMixtures: nasic - Nasenspray 10 mg/500 mg, XYLAZOL PEDİYATRİK 0,5 MG/ML + 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 10 MLMoxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalBayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Synonyms: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acidMixtures: Ixoba M, MOXİDEXA % 0,5 + % 0,1 GÖZ DAMLASI, ÇÖZELTİ, 1 ADETPhenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approved[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications … [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219]
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5,5-Diphenyltetrahydro-1H-2,4-imidazoledione, 5,5-diphenyltetrahydro-1H-2,4-imidazoledionePudexacianinium
go.drugbank.com/drugs/DB19161InvestigationalPudexacianinium is under investigation in clinical trial NCT05754333 (A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery).
Synonyms: )ETHYLIDENE)-2-METHOXYCYCLOHEX-1-EN-1-YL)ETHEN-1-Y, )-1,1-dimethyl-1h-benz(e)indolium ion