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Selenium
go.drugbank.com/drugs/DB11135ApprovedInvestigationalVet approvedSelenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen
Mixtures: Omega-3 Rx Complete, Multi Nt-OXCategories: Compounds used in a research, industrial, or household settingCamphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnIt appears in the list of drug products withdrawn or removed from the market for safety or effectiveness. … The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%.
Synonyms: Camphor D-form, (R)-camphorMixtures: Thunas Salve for Rheumatic Pains, CHAP ICE (R) MEDICATEDFosinopril
go.drugbank.com/drugs/DB00492ApprovedInvestigationalIt is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals
Categories: Agents Acting on the Renin-Angiotensin System, Antihypertensive Agents Indicated for HypertensionProducts: FOSINOPRIL Na, Lin-fosinoprilCabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigational[A7056] Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel]. … [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376]
Products: JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION, JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION)Isoflurane
go.drugbank.com/drugs/DB00753ApprovedInvestigationalVet approvedA stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Products: Isoflurane, (Volatile for Inhalation), Forane Liq InhZinc chloride
go.drugbank.com/drugs/DB14533ApprovedZinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes.
Mixtures: ADDAMEL N FOR INFUSION, Addamel NCategories: Compounds used in a research, industrial, or household setting, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseCarmustine
go.drugbank.com/drugs/DB00262ApprovedInvestigationalIt is used in the treatment of brain tumors and various other malignant neoplasms. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).
Synonyms: N,N'-Bis(2-chloroethyl)-N-nitrosoureaProducts: Carmustine for Injection USP, BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACKMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigationalMorphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … Morphine was granted FDA approval in 1941.[L12114]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diolEftrenonacog alfa
go.drugbank.com/drugs/DB11608ApprovedIt is an X-linked genetic disease caused by mutation of the gene for coagulation protein factor IX (FIX), leading to decreased levels of endogenous factor IX and increased susceptibility to recurrent bleeding … Eftrenonacog alfa treatment demonstrated good tolerability with no reports of inhibitor development in clinical studies [A31556].
Synonyms: Recombinant human coagulation factor IX, FC Fusion protein, Coagulation factor IX recombinant immunoglubulin g1 fusion proteinProducts: ALPROLIX® 250 UIPolatuzumab vedotin
go.drugbank.com/drugs/DB12240ApprovedInvestigationalPolatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. … [L6658] Polatuzumab vedotin was granted accelerated FDA approval on June 10, 2019 [A254936] and was approved by Health Canada on July 9, 2020.[L44141]
Products: POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 140MG, POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 30MG