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Glutathione synthetase
go.drugbank.com/bio_entities/BE0000185TargetHumansCatalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner (PubMed:7646467, PubMed:9215686). Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in li...
Synonyms: GSH-SVitronectin
go.drugbank.com/bio_entities/BE0001068TargetHumansVitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adh...
Synonyms: S-proteinAnamorsin homolog
go.drugbank.com/bio_entities/BE0009259TargetPlasmodium falciparum (isolate 3D7)Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. … Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.
Synonyms: Fe-S cluster assembly protein DRE2 homologPuromycin-sensitive aminopeptidase
go.drugbank.com/bio_entities/BE0003419TargetHumansAminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway f...
Synonyms: AAP-STerbinafine
go.drugbank.com/drugs/DB00857ApprovedInvestigationalVet approvedTerbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. … [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall
Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineMixtures: Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%, Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1%Metronidazole
go.drugbank.com/drugs/DB00916ApprovedInvestigationalMetronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. … [L3754] It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.
Synonyms: 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole, 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrroleInternational brands: Tricowas BOstrea edulis shell
go.drugbank.com/drugs/DB14251InvestigationalOstrea edulis shell is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: European Flat Oyster ShellAdult Onset Still's Disease
go.drugbank.com/conditions/DBCOND0136303Drugs: CanakinumabSynonyms: Adult-Onset Still´s DiseaseLaminin subunit alpha-1
go.drugbank.com/bio_entities/BE0002108TargetHumansBinding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. As a li...
Synonyms: S-LAM alpha, S-laminin subunit alphaClobetasol propionate
go.drugbank.com/drugs/DB01013ApprovedInvestigationalClobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.
Synonyms: Clobetasol propionate E, 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionateInternational brands: Embeline E