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Displaying results 7681 - 7690 of 10000 in total
  1. Drug

    Mevastatin

    go.drugbank.com/drugs/DB06693
    Experimental

    Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself. … Mevastatin or compactin is a cholesterol-lowering agent isolated from <i>Penicillium citinium</i>.

  2. Drug

    Isometheptene

    go.drugbank.com/drugs/DB06706
    Approved

    Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.

    Mixtures: CAFETRIN ®, ANTIALGINA®Categories: Adrenergic alpha-1 Receptor Agonists
  3. Drug

    Levonordefrin

    go.drugbank.com/drugs/DB06707
    ApprovedInvestigational

    Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.

    Synonyms: L-Nordefrin, L-alpha-methylnoradrenalineMixtures: Scandonest L, Scandonest 2% L
  4. Drug

    Lumefantrine

    go.drugbank.com/drugs/DB06708
    ApprovedInvestigational

    </i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas. … This combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.

    Synonyms: 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol, (±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanolMixtures: KOMEFAN ® 280, ARTEMETERO Y LUMEFANTRINA
  5. Drug

    Nilvadipine

    go.drugbank.com/drugs/DB06712
    Approved

    Nilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: Tensan retard 8 mg - Kapseln
  6. Drug

    Velaglucerase alfa

    go.drugbank.com/drugs/DB06720
    Approved

    Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. … Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.

    Synonyms: GA-GCBProducts: VPRIV ®, VPRIV 400 ÜNİTE İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 5 ADET
  7. Drug

    Aniline

    go.drugbank.com/drugs/DB06728
    Investigational

    Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. … Aniline is colorless, but it slowly oxidizes and resinifies in air, giving a red-brown tint to aged samples.

    Synonyms: Fentanyl impurity F, Trimethoprim specified impurity KCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Substrates
  8. Drug

    Gestodene

    go.drugbank.com/drugs/DB06730
    Investigational

    Gestodene is a progestogen hormonal contraceptive.

    Mixtures: FEMIANE®, FEMIANE®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  9. Drug

    beta-Naphthoflavone

    go.drugbank.com/drugs/DB06732
    Experimental

    It may be a chemopreventive agent. … β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs).

    Synonyms: 3-phenyl-1H-naphtho(2,1-b)pyran-1-one, β-NFCategories: Cytochrome P-450 CYP1A2 Inducers, Heterocyclic Compounds, 1-Ring
  10. Drug

    Bafilomycin A1

    go.drugbank.com/drugs/DB06733
    Experimental

    This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis. … The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus.