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Sodium fluorophosphate
go.drugbank.com/drugs/DB09484ApprovedInvestigationalSodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Synonyms: Na MFPMixtures: Hawaiian Airline EC with Colgate Toothbrush and Sun, Exoden All In OneDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalIn 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. … [A182411] Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some cases, is used to manage
Products: DONEPEZIL EG, DONEPEZIL AL 5 MGIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[L50181, L50186, L50201] Irinotecan liposome was approved by the FDA in February 2024.[L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I. … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic activity, thereby interfering with DNA synthesis.
Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, UGT1A9 Substrates with a Narrow Therapeutic IndexProducts: DARITEX-AAvelumab
go.drugbank.com/drugs/DB11945ApprovedInvestigationalAvelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. … [A261496] Avelumab was first approved by the FDA on March 23, 2017.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsGlycine
go.drugbank.com/drugs/DB00145ApprovedInvestigationalNutraceuticalVet approvedA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Mixtures: AA-Ven, Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose InjecProducts: GLICINA IRRIGACION AL 1.5%MASTER MEDICALDocetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigational[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and promote to cell death. … [L46466] Docetaxel was approved by the FDA in 1996 and is available in solution for injection for intravenous or parenteral administration.[A259676]
Synonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxolCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexCupric oxide
go.drugbank.com/drugs/DB11134ApprovedCupric oxide is used as a precursor in many copper-containing products such as wood preservatives and ceramics. … Cupric oxide may be found in over-the-counter vitamin-mineral supplements as a source of [DB09130]. The mean daily dietary intake of copper in adults ranges between 0.9 and 2.2 mg [L2422].
Mixtures: PNV 27-Ca/Fe/FA, SetonET-ECLamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalA reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.
Mixtures: N/A, N/ACategories: Antivirals used in combination for the treatment of HIV infectionsIpratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigationalIpratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent. … ] was approved in 1996.
Mixtures: Combivent nebuliser solution in unit dose vial, Duovent Nebuliser solution in Unit Dose Vial 4mlProducts: ATROVENT N METERED DOSE INHALER 20 mcg/puff, ATROVENT N METERED DOSE INHALER 20MCG/PUFFEucalyptus oil
go.drugbank.com/drugs/DB11114ApprovedIt is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. … Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus.
Mixtures: La Vaquita, La Vaquita Extra Strength