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Displaying results 761 - 770 of 10000 in total
  1. Drug

    Rilpivirine

    go.drugbank.com/drugs/DB08864
    ApprovedInvestigational

    [A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. … [L1030] On November 21, 2017, Rilpivirine, in combination with [dolutegravir], was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named

    Synonyms: 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrileMixtures: ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET, ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 30 ADET
  2. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    [L36325] Filgrastim-sndz was approved on March 6, 2015 [L40768] and filgrastim-ayow was approved on March 2, 2022. … It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_.

    Products: NIVESTIM 30 MU/0,5 ML SC/IV ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR ENJEKTÖR, 10 ADET, LEUKOPLUS 30 MIU/ML SC/IV ENJEKSIYON/INFUZYON ICIN COZ. ICEREN FLAKON, 10 ADET
  3. Drug

    Calcium lactate

    go.drugbank.com/drugs/DB13231
    ApprovedVet approved

    Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener [L2741]. … Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.

    Synonyms: Calcium 2-hydroxypropanoate (1:2), 2-Hydroxypropanoic acid calcium saltMixtures: FOSFO KALSIYUM GRANULE, 200 G, Cal M Tab
  4. Drug

    Diphenoxylate

    go.drugbank.com/drugs/DB01081
    ApprovedIllicitInvestigational

    Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. … When diphenoxylate is used alone, it is classified as a Schedule II.

    Mixtures: LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 MLCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Alfuzosin

    go.drugbank.com/drugs/DB00346
    Approved

    The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to 80%-90% of those over 70. … [L31593] It was initially approved by the FDA in 2003 and is marketed by several pharmaceutical companies.[L9251]

    Categories: Heterocyclic Compounds, 2-Ring, Peripheral alpha-1 blockersSynonyms: (±)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furamide, N-[3-[(4-amino-6,7-dimethoxy-quinazolin-2-yl)- methyl-amino]propyl] tetrahydrofuran- 2-carboxamide
  6. Drug

    Dicyclomine

    go.drugbank.com/drugs/DB00804
    ApprovedInvestigational

    [L7982] Dicyclomine was granted FDA approval on 11 May 1950.[L7967] … Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder

    Mixtures: แอนพัส 520Synonyms: 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate, Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester
  7. Drug

    Phenolphthalein

    go.drugbank.com/drugs/DB04824
    ApprovedWithdrawn

    Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.

    Mixtures: Herbalax Forte No 70 Tab, AGAROL M (EMULSION)Synonyms: 3,3-Bis(4-hydroxyphenyl)phthalide
  8. Indication

    Uncontrolled with <1.8 mg daily liraglutide

    go.drugbank.com/conditions/DBCOND0106443
    Drugs: Insulin degludec
    Synonyms: Uncontrolled with <1.8 mg daily liraglutide
  9. Drug

    Vildagliptin

    go.drugbank.com/drugs/DB04876
    ApprovedInvestigational

    Elevated levels of GLP-1 and GIP consequently results in improved glycemic control.[L32803] In clinical trials, vildagliptin has a relatively low risk of hypoglycemia. … [A232488] By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are incretin hormones that promote

    Mixtures: VILMET 50 MG/1000 MG FILM KAPLI TABLET ,1TABLET, 20 ADET, VILMET 50 MG/850 MG FILM KAPLI TABLET ,1TABLET, 120 ADETCategories: Glucagon-Like Peptide 1, Heterocyclic Compounds, 1-Ring
  10. Drug

    Ribavirin

    go.drugbank.com/drugs/DB00811
    ApprovedInvestigational

    The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks in patients with genotype 2 and 3 [A19626]. … Combination therapy of ribavirin and [DB00008] results in the SVR of 44% in patients with genotype 1 infection and 70% in patients with genotype 2-6.

    Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules), Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules)Synonyms: 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide