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Icatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … [A4017,A263041] It was investigated as a potential treatment of hereditary angioedema (HAE) as bradykinin was implicated in HAE swelling; specifically, mice lacking B<sub>2</sub> receptors showed reduced
Categories: Drugs Used in Hereditary AngioedemaProducts: ICATIBANT DR. REDDY'S, Icatibant Reddy 30 mg/3 ml Injektionslösung in einer FertigspritzeAcyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigational[L7321] Acyclovir was granted FDA approval on 29 March 1982.[L7318] … [L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old.
Mixtures: HERPAZON % 5 + % 1 KREM, 5 GRAM, Activir Duo 50 mg/g + 10 mg/g CremeCategories: MATE 1 Substrates, MATE 2 SubstratesSelenium Sulfide
go.drugbank.com/drugs/DB00971ApprovedSelenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent … Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea.
Synonyms: Selenium(IV) sulfide, Selenium(IV) sulphideProducts: Selsun Blue 2-in-1, Selsun Blue, 2-IN-1Anastrozole
go.drugbank.com/drugs/DB01217ApprovedInvestigationalAnastrozole is a non-steroidal aromatase inhibitor (AI), similar to [letrozole], used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer … [L8863] Anastrozole is also related to [exemestane], a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrileRitodrine
go.drugbank.com/drugs/DB00867ApprovedWithdrawnAdrenergic beta-agonist used to control premature labor.
Categories: Adrenergic beta-2 Receptor AgonistsSynonyms: p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcoholPaclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedUsed as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel … Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine, Taxol AHydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedIn April 2023, the FDA withdrew its approval of Makena and its generics given an unfavorable risk-to-benefit assessment.[L46113] … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy
Mixtures: GRAVIDINONA 2 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InducersMethylprednisolone hemisuccinate
go.drugbank.com/drugs/DB14644ApprovedInvestigationalA water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP3A InducersProducts: SOLU-MEDROL DE 40 MG SOLUCION, METICURE 20 MG IM/IV ENJEKSIYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADETTyphoid Vi polysaccharide vaccine
go.drugbank.com/drugs/DB10803ApprovedInvestigationalIt is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older. … Typhoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly.
Synonyms: Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain, Typhoid Vi polysaccharide vaccineProducts: TYPHIM VI 0,5 ML IM/SC ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, Typhim VI Solution for Injection in MultidoseLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigationalLetrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990. … [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623]
Mixtures: Kisqali Femara Co-pack, Kisqali Femara Co-packCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates