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Collagen alpha-2(I) chain
go.drugbank.com/bio_entities/BE0002141TargetHumansType I collagen is a member of group I collagen (fibrillar forming collagen)
Polypeptides: Collagen alpha-2(I) chainSynonyms: Alpha-2 type I collagenCalcineurin subunit B type 2
go.drugbank.com/bio_entities/BE0002143TargetHumansRegulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity
Polypeptides: Calcineurin subunit B type 2Synonyms: Protein phosphatase 2B regulatory subunit 2Protein-arginine deiminase type-2
go.drugbank.com/bio_entities/BE0002316TargetHumansCatalyzes the deimination of arginine residues of proteins
Polypeptides: Protein-arginine deiminase type-2Neuropeptide Y receptor type 2
go.drugbank.com/bio_entities/BE0002419TargetHumansReceptor activation by ligands also leads to an increase of intracellular Ca(2+) levels (PubMed:7559383, PubMed:7592910).
Polypeptides: Neuropeptide Y receptor type 2Immunoglobulin lambda variable 2-8
go.drugbank.com/bio_entities/BE0002939TargetHumansV region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Polypeptides: Immunoglobulin lambda variable 2-8Autoinducer 2-binding protein LsrB
go.drugbank.com/bio_entities/BE0003287TargetSalmonella typhiPart of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
Polypeptides: Autoinducer 2-binding protein LsrBSynonyms: AI-2-binding protein LsrBGamma-secretase subunit PEN-2
go.drugbank.com/bio_entities/BE0003410TargetHumansEssential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:12522139, PubMed:1...
Polypeptides: Gamma-secretase subunit PEN-2Synonyms: Presenilin enhancer protein 2Bcl-2-like protein 1
go.drugbank.com/bio_entities/BE0003510TargetHumansPotent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the m...
Polypeptides: Bcl-2-like protein 1Poly [ADP-ribose] polymerase 2
go.drugbank.com/bio_entities/BE0003798TargetHumansIn addition to proteins, also able to ADP-ribosylate DNA: preferentially acts on 5'-terminal phosphates at DNA strand breaks termini in nicked duplex (PubMed:27471034, PubMed:29361132) … aspartate or serine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'
Polypeptides: Poly [ADP-ribose] polymerase 2Synonyms: ADPRT-2, PARP-2Immunoglobulin kappa variable 2-30
go.drugbank.com/bio_entities/BE0003837TargetHumansV region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Polypeptides: Immunoglobulin kappa variable 2-30