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Displaying results 7771 - 7780 of 10000 in total
  1. Drug

    Serabelisib

    go.drugbank.com/drugs/DB14935
    Investigational

    Serabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics … of TAK-117 (MLN1117) in Healthy Participants).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    Siagoside

    go.drugbank.com/drugs/DB12351
    Investigational

    It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair. … Treatment results in a 52% decrease in mortality 48 hours after the induction of ischemia in gerbils by permanent unilateral ligation of the common carotid artery.

  3. Drug

    Phosphoaminophosphonic Acid-Adenylate Ester

    go.drugbank.com/drugs/DB04395
    Experimental

    5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. … It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]

  4. Drug

    Famprofazone

    go.drugbank.com/drugs/DB16702
    Experimental

    Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. … [L34724] It is important to note that the drug is metabolized to [methamphetamine] and [amphetamine] in the body and can lead to positive tests results for illicit drug use.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Bimosiamose

    go.drugbank.com/drugs/DB06197
    Investigational

  6. Drug

    VTX-801

    go.drugbank.com/drugs/DB17646
    Investigational

    It is being investigated in Wilson Disease.[L45924] … VTX-801 is a replication-deficient recombinant adeno-associated viral vector (rAAV) consisting of an AAV liver tropic capsid containing a single-stranded DNA genome carrying a shortened version of the

  7. Drug

    Trenbolone

    go.drugbank.com/drugs/DB11551
    ExperimentalVet approved

    Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone. … Trenbolone, also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and appetite.

    Synonyms: 17-b-Hydroxyestra-4,9,11-trien-3-one, 17-β-hydroxyestra-4,9,11-trien-3-one
  8. Drug

    Imidocarb

    go.drugbank.com/drugs/DB11521
    ExperimentalVet approved

    Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.

    Synonyms: N,N'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea, 1,3-Bis(3-(2-imidazolin-2-yl)phenyl)harnstoff
  9. Drug

    Adafosbuvir

    go.drugbank.com/drugs/DB14906
    Investigational

    Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Methylprednisone

    go.drugbank.com/drugs/DB12952
    ApprovedInvestigationalWithdrawn

    Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 6-alpha-methylprednisone