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Displaying results 771 - 780 of 6949 in total
  1. Drug

    Castor oil

    go.drugbank.com/drugs/DB11113
    ApprovedNutraceuticalVet approved

    It is an FDA-approved food additive directly added to food products for human consumption. … [DB02955] has a hydroxyl group that provides a functional group location for various chemical reactions, making it a favourable substance in industrial applications [A31170].

    Categories: Drugs for Constipation
  2. Drug

    Famtozinameran

    go.drugbank.com/drugs/DB17088
    ApprovedInvestigational

    It is administered in combination with [tozinameran] for active immunization against COVID-19 caused by SARS-CoV-2, including infection caused by Omicron BA.4/BA.5.[L43907,L43912]

  3. Drug

    Probucol

    go.drugbank.com/drugs/DB01599
    ApprovedInvestigationalWithdrawn

    A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).

  4. Target

    Leucine-rich repeat-containing G protein-coupled receptor 5

    go.drugbank.com/bio_entities/BE0010835
    TargetHumans

    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle.

    Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5Synonyms: G protein-coupled receptor 49, G protein-coupled receptor 67
  5. Drug

    Bretylium

    go.drugbank.com/drugs/DB01158
    Approved

    Recent evidence has shown that bretylium may also inhibit the Na,K-ATPase by binding to the extracellular K-site. … The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels.

  6. Indication

    Deficiency of the interleukin-1 receptor antagonist

    go.drugbank.com/conditions/DBCOND0008480
    Drugs: Anakinra · Rilonacept
    Synonyms: Deficiency of interleukin-1 receptor antagonist, Interleukin-1 receptor antagonist deficiency
  7. Indication

    Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer

    go.drugbank.com/conditions/DBCOND0111347
    Drugs: Vepdegestrant
    Synonyms: Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer
  8. Indication

    Early Stage Estrogen Receptor (ER) Positive Breast Cancer

    go.drugbank.com/conditions/DBCOND0068305
    Drugs: Tamoxifen
    Synonyms: Early Stage Estrogen Receptor (ER) Positive Breast Cancer
  9. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

  10. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    Nevertheless, it is because of this mechanism that sildenafil is also indicated for treating pulmonary arterial hypertension but is also additionally notorious for interacting with various anti-anginal … Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common and effective treatment for erectile dysfunction and since its formal approval for medical use in

    Products: Sildenafil for Oral Suspension