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Arsenite methyltransferase
go.drugbank.com/bio_entities/BE0005015TargetEnzymeHumansCatalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals (PubMed:16407288, PubMed:25997655). It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is redu...
Synonyms: S-adenosyl-L-methionine:arsenic(III) methyltransferaseATP-citrate synthase
go.drugbank.com/bio_entities/BE0009867TargetEnzymeHumansCatalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate in multiple biochemical reactions in protein, carbohydrate and lipid metabolism
Synonyms: ATP-citrate (pro-S-)-lyaseMinoxidil
go.drugbank.com/drugs/DB00350ApprovedInvestigationalA potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Mixtures: MINOXIDIL 7% / NIACINAMIDE 4% s, FluMisch 5% MinoxidilCategories: Heterocyclic Compounds, 1-RingMaralixibat
go.drugbank.com/drugs/DB16226ApprovedInvestigational[L38834] Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, [rifampin], [ursodeoxycholic acid], [cholestyramine], [naltrexone], and [sertraline … Use (CHMP) recommended maralixibat be granted marketing authorization for the treatment of cholestatic pruritus in patients with Alagille syndrome:[L43547] it was granted marketing authorization in Europe
Categories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 2-RingCreatine Kinases
go.drugbank.com/bio_entities/BE0009627EnzymeTargetHumansReversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) (PubMed:8186255). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energ...
Synonyms: S-MtCKPolypeptides: Creatine kinase S-type, mitochondrialPovidone-iodine
go.drugbank.com/drugs/DB06812ApprovedInvestigationalThis unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.
Mixtures: Percutaneous Sheath Intro Kit Ak-09810-S, Percutaneous Sheath Intro Kit Ak-09810-SCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingHodgkin's Lymphoma
go.drugbank.com/conditions/DBCOND0030382Drugs: Bleomycin · Chlorambucil · Cyclophosphamide · Dacarbazine · Doxorubicin · Gemcitabine +5 moreSynonyms: Hodgkin´s Lymphomas, Hodgkin´s LymphomaQuinoprotein glucose dehydrogenase B
go.drugbank.com/bio_entities/BE0001728TargetEnzymeAcinetobacter calcoaceticusOxidizes glucose to gluconolactone.
Synonyms: s-GDHHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approvedHydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574]
Synonyms: Kendall's compound F, Reichstein's substance MInternational brands: Polcort H, Preparation H Hydrocortisone CreamNalmefene
go.drugbank.com/drugs/DB06230ApprovedInvestigationalWithdrawnNalmefene, a 6-methylene analogue of [naltrexone], is an opioid receptor antagonist. … [L1024] In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence.
Synonyms: MORPHINAN-3,14-DIOL, 17-(CYCLOPROPYLMETHYL)-4,5-EPOXY-6-METHYLENE-, (5.ALPHA.)-, 17-(Cyclopropylmethyl)-4,5α-epoxy-6-methylenemorphinan-3,14-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates