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Repulsive guidance molecule A
go.drugbank.com/bio_entities/BE0018257TargetHumansIt also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8 … Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite
Polypeptides: Repulsive guidance molecule ASynonyms: RGM domain family member APoly(A) polymerase gamma
go.drugbank.com/bio_entities/BE0018981TargetHumansResponsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA
Polypeptides: Poly(A) polymerase gammaSynonyms: Neo-poly(A) polymeraseLipid A palmitoyltransferase PagP
go.drugbank.com/bio_entities/BE0001965TargetEscherichia coli (strain K12)Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
Polypeptides: Lipid A palmitoyltransferase PagPSynonyms: Lipid A acylation proteinDihydroorotate dehydrogenase A (fumarate)
go.drugbank.com/bio_entities/BE0002008TargetLactococcus lactis subsp. cremorisCatalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
Polypeptides: Dihydroorotate dehydrogenase A (fumarate)Synonyms: DHOD ABCL11 transcription factor A
go.drugbank.com/bio_entities/BE0019545TargetHumansMay function as a modulator of the transcriptional repression activity of NR2F2 (By similarity) … May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity).
Polypeptides: BCL11 transcription factor ACholine-phosphate cytidylyltransferase A
go.drugbank.com/bio_entities/BE0000615EnzymeTargetHumansCatalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis
Polypeptides: Choline-phosphate cytidylyltransferase ASynonyms: CCT A, CT ACatabolite control protein A
go.drugbank.com/bio_entities/BE0001530TargetBacillus megateriumGlobal transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.
Polypeptides: Catabolite control protein AFructose-bisphosphate aldolase A
go.drugbank.com/bio_entities/BE0001683TargetEnzymeHumansIn addition, also functions as a scaffolding protein (By similarity). … Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis (PubMed:14766013).
Polypeptides: Fructose-bisphosphate aldolase AOuter membrane protein A
go.drugbank.com/bio_entities/BE0002043TargetEscherichia coli (strain K12)Plays a role in resistance to environmental stress, and a role in outer membrane functionality and cell shape (PubMed:11906175, PubMed:361695). … A very abundant protein, there can be up to 210,000 OmpA molecules per cell (PubMed:24766808).
Polypeptides: Outer membrane protein ASynonyms: Outer membrane porin A