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Lubiprostone
go.drugbank.com/drugs/DB01046ApprovedInvestigationalActivation of these channels promotes the secretion of a chloride-rich fluid that soften the stool, increase gastrointestinal motility, and induce spontaneous bowel movements (SBM).
Proteasome subunit beta type-6
go.drugbank.com/bio_entities/BE0003919TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Synonyms: Multicatalytic endopeptidase complex delta chainN-lysine methyltransferase KMT5A
go.drugbank.com/bio_entities/BE0019990TargetHumansNucleosomes are preferred as substrate compared to free histones (PubMed:12086618, PubMed:12121615, PubMed:15200950, PubMed:15933069, PubMed:15933070, PubMed:15964846, PubMed:16517599).
Synonyms: SET domain-containing protein 8, PR/SET domain-containing protein 07Dienestrol
go.drugbank.com/drugs/DB00890ApprovedWithdrawnDienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen r...
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemHydroquinone
go.drugbank.com/drugs/DB09526ApprovedInvestigationalHydroquinone has come under scrutiny due to several complications associated with its use, including dermal irritation, exogenous onchronosis, and carginogenicity.
Mixtures: Nu-derm Starter Set Normal-dry Skin Transformation System, Nu-derm Starter Set Normal-dry Skin Transformation SystemProducts: Skin Lightening Complex, Essential Fade ComplexBuprenorphine
go.drugbank.com/drugs/DB00921ApprovedIllicitInvestigationalVet approved[A186263,A186266,A186269] Buprenorphine acts as a partial mu-opioid receptor agonist with a high affinity for the receptor, but lower intrinsic activity compared to other full mu-opioid agonists such … This effect can be beneficial, however, as dose-related side effects such as respiratory depression, sedation, and intoxication also plateau at around 32mg, resulting in a lower risk of overdose compared
Camostat
go.drugbank.com/drugs/DB13729InvestigationalCamostat mesylate, or FOY-305, is a synthetic serine protease inhibitor. It was first described in the literature in 1981, as part of research on the inhibition of skin tumors in mice. Camostat mesylate inhibits cholecystokinin, pro-infl...
Amaranthus retroflexus whole
go.drugbank.com/drugs/DB10930ApprovedAmaranthus retroflexus whole allergenic extract is used in allergenic testing.
Mixtures: Treatment Set TS345380DNA polymerase epsilon subunit 3
go.drugbank.com/bio_entities/BE0003617TargetHumansDoes not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (PubMed:14759371) … Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity).
Synonyms: Chromatin accessibility complex 17 kDa proteinPhospholipid-transporting ATPase IC
go.drugbank.com/bio_entities/BE0011765TransporterHumansCatalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of phospholipids, in particular phosphatidylcholines (PC), from the outer to the inner
Synonyms: P4-ATPase flippase complex alpha subunit ATP8B1