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Iobenguane
go.drugbank.com/drugs/DB06704ApprovedInvestigationalThe radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. … Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008.
Categories: Compounds used in a research, industrial, or household settingMercaptopurine
go.drugbank.com/drugs/DB01033ApprovedInvestigationalIt interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Categories: Drugs for Obstructive Airway Diseases, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexCoagulation factor X human
go.drugbank.com/drugs/DB13148ApprovedInvestigationalIt is a two-chain glycoprotein with the molecular weight of approximately 59 kDa [A31472]. … However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe hereditary Factor X deficiency.
Mixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTIONXylometazoline
go.drugbank.com/drugs/DB06694Approved[A228508] Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies. … In some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol].
Mixtures: Ophtrivin A Ophthalmic Dps, nasic pur NasensprayProducts: XYLOMETAZOLIN0.1%NAS STA L, NASENGEL ALLanolin
go.drugbank.com/drugs/DB11112ApprovedLanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. … Lanolin primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides. For this reason, it is also called wool wax or wool grease.
Mixtures: Kendra SKIN PROTECTION and PAIN RELIEF FOR HAIR REMOVAL, Skullduggery Pain Relief and Skin Protection for TattoosCategories: Compounds used in a research, industrial, or household settingStrontium ranelate
go.drugbank.com/drugs/DB09267ApprovedWithdrawnStrontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. … Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an
Categories: Drugs for Treatment of Bone DiseasesProducts: PROTOS Granules for Oral Suspension 2gIbalizumab
go.drugbank.com/drugs/DB12698ApprovedInvestigationalIn October 2022, the FDA approved the administration of Trogarzo (ibalizumab-uiyk) by intravenous push, allowing for a faster drug administration.[L43443,L43448] … This drug was approved in March 2018 for the management of treatment-resistant HIV [L1554].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseBetrixaban
go.drugbank.com/drugs/DB12364ApprovedBetrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks … for VTE [A27285].
Categories: Factor Xa Inhibitors, Direct factor Xa inhibitorsInositol
go.drugbank.com/drugs/DB13178ApprovedInvestigationalWithdrawnIt is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate … Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol.
Synonyms: L-myo-InositolMixtures: Twin Opti Pwr, Formula Pro-BGolimumab
go.drugbank.com/drugs/DB06674ApprovedInvestigationalulcerative colitis (UC) who require chronic steroids or have experienced intolerance or only a partial response to previous medications. … Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate
Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: Concentrate for Solution for Infusion 12.5mg/1 ml, SIMPONI IV 12.5mg/1ml Concentrate for Solution for Infusion