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Displaying results 781 - 790 of 8412 in total
  1. Indication

    Menstrual Irregularities

    go.drugbank.com/conditions/DBCOND0054756
    Drugs: Cyproterone acetate · Estradiol benzoate · Estradiol valerate
  2. Drug

    Sitagliptin

    go.drugbank.com/drugs/DB01261
    ApprovedInvestigational

    Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256

    Mixtures: ARGLIPTIN-D, LIBERECO-DXCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  3. Drug

    Testosterone enanthate

    go.drugbank.com/drugs/DB13944
    ApprovedInvestigational

    Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. … s Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector [L4659].

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Apalutamide

    go.drugbank.com/drugs/DB11901
    ApprovedInvestigational

    Higher prostate-specific antigen (PSA) and shorter PSA doubling time (PSA DT) are associated with a higher risk for metastases and death [A31846]. … Exerting an antitumor action, apalutamide blocking the effect of androgens that promote tumor growth.

    Categories: P-glycoprotein inducers, Cytochrome P-450 Substrates
  5. Drug

    Technetium Tc-99m etifenin

    go.drugbank.com/drugs/DB13183
    Investigational

    Products: EHIDA KIT PARA LA PREPARACIÓN DE RADIOFÁRMACOS.
  6. Drug

    Piroxicam

    go.drugbank.com/drugs/DB00554
    ApprovedInvestigational

    A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its lon...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: VERAN-D, PIROXICAM DR. REDDY'S
  7. Drug

    Meglumine antimoniate

    go.drugbank.com/drugs/DB13732
    Investigational

    Synonyms: Antimoniato de megluminaProducts: ANTIMONIATO DE MEGLUMINE1.5 G/ 5ML
  8. Drug

    Ropeginterferon alfa-2b

    go.drugbank.com/drugs/DB15119
    ApprovedInvestigational

    Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for … [A242015, L39170] Ropeginterferon alfa-2b has shown efficacy in PV in _in vitro_ and _in vivo_ models and clinical trials.

    Synonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2bCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 Inhibitors
  9. Pathway

    Aromatase Deficiency

    smpdb.ca/view/SMP0000565
    Disease

    Aromatase deficiency is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of mutations in the CYP19A1 gene. The CYP19A1 gene encodes for the enzyme aromatase. Aromatase converts androgens to estrogens which is vita...

    Drugs: NADH · Testosterone · Estrone · Estradiol · Calcium · Androstenedione +6 more
    Enzymes: Estradiol 17-beta-dehydrogenase 1
  10. Drug

    Tamoxifen

    go.drugbank.com/drugs/DB00675
    ApprovedInvestigational

    [A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsSynonyms: 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene