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Displaying results 781 - 790 of 10000 in total
  1. Drug

    Norepinephrine

    go.drugbank.com/drugs/DB00368
    ApprovedInvestigational

    It is also found in plants and is used pharmacologically as a sympathomimetic. … Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus.

    Synonyms: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol, (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediolMixtures: XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUS
  2. Drug

    Vitamin E

    go.drugbank.com/drugs/DB00163
    ApprovedInvestigationalNutraceuticalVet approved

    In 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. … Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage[A176104].

    Synonyms: (2R,4'R,8'R)-α-tocopherolInternational brands: Aquasol E, Amino-Opti-E
  3. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    [L36325] Filgrastim-sndz was approved on March 6, 2015 [L40768] and filgrastim-ayow was approved on March 2, 2022. … It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_.

    Products: ZARZIO® 30 MU/0.5 ML SOLUCION INYECTABLE O PARA PERFUSION EN JERINGA PRECARGADA, NIVESTIM 30 MU/0,5 ML SC/IV ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR ENJEKTÖR, 10 ADET
  4. Drug

    Pamidronic acid

    go.drugbank.com/drugs/DB00282
    ApprovedInvestigational

    [A203111] Pamidronic acid was first described in the literature in 1977. … [A203111] Pamidronic acid was granted FDA approval on 31 October 1991.[L13835]

    Products: AREDIA 90 MG/10 ML FLAKON, 1 ADET, PAMISOL CONCENTRATED INJECTION 90 mg/10 ml
  5. Drug

    Betamethasone

    go.drugbank.com/drugs/DB00443
    ApprovedInvestigationalVet approved

    Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states inclu...

    Mixtures: FUCICORT 20 MG/G + 1 MG/G KREM, 30 G, Fusicutan 20 mg/g + 1 mg/g CremeSynonyms: 16β-Methyl-1,4-pregnadiene-9α-fluoro-11β,17α,21-triol-3,20-dione
  6. Drug

    Celecoxib

    go.drugbank.com/drugs/DB00482
    ApprovedInvestigational

    [L7604] Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies … Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other

    Categories: Cyclooxygenase-2 (COX-2) Inhibitors, COX-2 InhibitorsSynonyms: p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
  7. Drug

    Dexmedetomidine

    go.drugbank.com/drugs/DB00633
    ApprovedInvestigationalVet approved

    An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

    Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsProducts: DEXMEDETOMIDINA 0.2 MG/ 2 ML SOLUCION INYECTABLE, SEMOTİDİN 200 MCG/50 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET
  8. Drug

    Everolimus

    go.drugbank.com/drugs/DB01590
    ApprovedInvestigational

    In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein. … It is currently used as an immunosuppressant to prevent rejection of organ transplants.

    Synonyms: 40-O-(2-hydroxyethyl)-rapamycin, 42-O-(2-Hydroxyethyl)rapamycinProducts: EVEROLIMUS EG, AFINITOR (10 MG)
  9. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation. … and use, including the development of orally soluble films that are both discreet in administration and less of a burden in comparison to having patients attempt to swallow pills during emesis.

    Products: ONZYD 4 MG AGIZDA DAGILAN 10 TABLET, ONZYD 8 MG AGIZDA DAGILAN 10 TABLET
  10. Drug

    Roxithromycin

    go.drugbank.com/drugs/DB00778
    ApprovedInvestigationalWithdrawn

    It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections.

    Synonyms: (9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)International brands: Le Er Tai, Roxl-150