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Displaying results 781 - 790 of 1186 in total
  1. Target

    Short transient receptor potential channel 1

    go.drugbank.com/bio_entities/BE0013282
    TargetHumans

    Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:11139478, PubMed:15016832, PubMed:39478185).

    Polypeptides: Short transient receptor potential channel 1Synonyms: Transient receptor protein 1
  2. Target

    Interleukin-12 receptor subunit beta-2

    go.drugbank.com/bio_entities/BE0018860
    TargetHumans

    Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells.

    Polypeptides: Interleukin-12 receptor subunit beta-2Synonyms: IL-12 receptor subunit beta-2
  3. Target

    Taste receptor type 2 member 10

    go.drugbank.com/bio_entities/BE0020463
    TargetHumans

    Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.

    Polypeptides: Taste receptor type 2 member 10Synonyms: Taste receptor family B member 2
  4. Target

    Short transient receptor potential channel 4

    go.drugbank.com/bio_entities/BE0020751
    TargetHumans

    Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:11042129, PubMed:11713258, PubMed:16144838, PubMed:39478185).

    Polypeptides: Short transient receptor potential channel 4
  5. Target

    Short transient receptor potential channel 5

    go.drugbank.com/bio_entities/BE0021113
    TargetHumans

    Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:16284075, PubMed:38959890, PubMed:37137991).

    Polypeptides: Short transient receptor potential channel 5Synonyms: Transient receptor protein 5
  6. Target

    Taste receptor type 2 member 14

    go.drugbank.com/bio_entities/BE0023216
    TargetHumans

    Gustducin-linked G protein-coupled receptor that plays a role in the perception of bitterness (PubMed:38600377, PubMed:38776963). … The activity of this receptor stimulates GNAT3, activating the gustducin G protein pathway (PubMed:38600377, PubMed:38776963).

    Polypeptides: Taste receptor type 2 member 14Synonyms: Taste receptor family B member 1
  7. Drug

    Dihydroergotamine

    go.drugbank.com/drugs/DB00320
    ApprovedInvestigational

    Recent improvements have been made in the design of intranasal delivery devices allowing for greater delivery of dihydroergotamine solution to the vasculature-rich upper nasal cavity.

    Categories: Serotonin Receptor Agonists, Adrenergic alpha-1 Receptor Antagonists
  8. Drug

    Pemivibart

    go.drugbank.com/drugs/DB18720
    Investigational

    Pemivibart (Pemgarda) is a human IgG1 monoclonal antibody targeting the SARS-CoV-2 spike protein receptor binding domain.

  9. Indication

    Anticholinergic Syndrome

    go.drugbank.com/conditions/DBCOND0005987
    Drugs: Physostigmine
    Synonyms: Poisoning caused by acetylcholine receptor antagonist, Poisoning caused by acetylcholine receptor antagonist (disorder)
  10. Drug

    Afamelanotide

    go.drugbank.com/drugs/DB04931
    Approved

    [L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125]

    Categories: Melanocortin Receptor Agonists, Melanocortin 1 Receptor (MC1-R) Agonists