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Displaying results 71 - 80 of 446 in total
  1. Target

    Delta-aminolevulinic acid dehydratase

    go.drugbank.com/bio_entities/BE0002002
    TargetEscherichia coli (strain K12)

    Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.

    Polypeptides: Delta-aminolevulinic acid dehydratase
  2. Target

    N-succinylamino acid racemase

    go.drugbank.com/bio_entities/BE0003211
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Catalyzes both N-succinylamino acid racemization and OSB synthesis at equivalent rates (PubMed:24872444). … Acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-L-phenylglycine and N-succinyl-D/L-phenylalanine (PubMed:24872444, PubMed:25875730).

    Polypeptides: N-succinylamino acid racemaseSynonyms: N-acylamino acid racemase, o-succinylbenzoic acid synthase
  3. Target

    D-Amino acid amidase

    go.drugbank.com/bio_entities/BE0004262
    TargetOchrobactrum anthropi

    Polypeptides: D-Amino acid amidase
  4. Target

    Retinoic acid receptor gamma

    go.drugbank.com/bio_entities/BE0000144
    TargetHumans

    Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes … In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity)

    Polypeptides: Retinoic acid receptor gamma
  5. Target

    Aromatic-amino-acid aminotransferase

    go.drugbank.com/bio_entities/BE0001389
    TargetParacoccus denitrificans

    Shows activities toward both dicarboxylic and aromatic substrates.

    Polypeptides: Aromatic-amino-acid aminotransferase
  6. Target

    D-amino-acid oxidase

    go.drugbank.com/bio_entities/BE0004141
    TargetEnzymeHumans

    Regulates the level of D-amino acid neurotransmitters in the brain, such as D-serine, a co-agonist of N-methyl D-aspartate (NMDA) receptors, and may modulate synaptic transmission (PubMed:17303072). … Required to catabolize D-amino acids synthesized endogenously, of gastrointestinal bacterial origin or obtained from the diet, and to use these as nutrients (By similarity).

    Polypeptides: D-amino-acid oxidaseFunction: D-amino-acid dehydrogenase activity
  7. Target

    L-amino-acid oxidase

    go.drugbank.com/bio_entities/BE0004566
    TargetHumans

    Has preference for L-aromatic amino acids: converts phenylalanine (Phe), tyrosine (Tyr) and tryptophan (Trp) to phenylpyruvic acid (PP), hydroxyphenylpyruvic acid (HPP), and indole-3-pyruvic acid (I3P) … IL4I1-mediated Trp catabolism generates I3P, giving rise to indole metabolites (indole-3-acetic acid (IAA) and indole-3-aldehyde (I3A)) and kynurenic acid, which act as ligands for AHR, a ligand-activated

    Polypeptides: L-amino-acid oxidaseFunction: L-amino-acid oxidase activity
  8. Target

    Lysophosphatidic acid receptor 1

    go.drugbank.com/bio_entities/BE0017535
    TargetHumans

    Receptor for lysophosphatidic acid (LPA) (PubMed:19306925, PubMed:25025571, PubMed:26091040, PubMed:9070858). … Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents.

    Polypeptides: Lysophosphatidic acid receptor 1Synonyms: Lysophosphatidic acid receptor Edg-2
  9. Target

    Delta-aminolevulinic acid dehydratase

    go.drugbank.com/bio_entities/BE0000050
    TargetEnzymeHumans

    Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen

    Polypeptides: Delta-aminolevulinic acid dehydratase
  10. Target

    Cysteine sulfinic acid decarboxylase

    go.drugbank.com/bio_entities/BE0000079
    TargetHumans

    Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. … Does not exhibit any decarboxylation activity toward glutamate

    Polypeptides: Cysteine sulfinic acid decarboxylase