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Isocarboxazid Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126692Drug actionThe first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … The monoamine oxidase is an enzyme that catalyzes the oxidative deamination of many amines like serotonin, norepinephrine, epinephrine, and dopamine. There are 2 isoforms of this protein: A and B.
Enzymes: Sodium-dependent noradrenaline transporterPhentermine Action Pathway
smpdb.ca/view/SMP0125178Drug actionThe overall effect of phentermine is to increase synaptic concentration of norepinephrine and inhibit its reuptake and metabolism. … Rare severe adverse events include atrial fibrillation, acute psychosis and pulmonary hypertension.
Enzymes: Sodium-dependent noradrenaline transporterAmine Oxidase Norepinephrine
smpdb.ca/view/SMP0130460Physiological) as well as toxins and carcinogens in foods and the environment. … The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine.
Enzymes: Sodium-dependent noradrenaline transporterTranylcypromine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126672Drug actionAn overdose of this drug will result in insomnia, restlessness, and anxiety. Hypotension, dizziness, weakness, and drowsiness may occur, progressing in severe cases to extreme dizziness and shock. … The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine.
Enzymes: Sodium-dependent noradrenaline transporterPhenelzine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126682Drug actionThis drug is used as an antidepressant and it is also effective in the treatment of panic disorder and social anxiety disorder. … The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine.
Enzymes: Sodium-dependent noradrenaline transporterMinaprine Amine oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126684Drug actionThe first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … Firstly, this drug binds as an antagonist to the serotonin type 2 receptors (C, B, and C). Secondly, it can also antagonize the dopamine D1 and D2 type receptors.
Enzymes: Sodium-dependent noradrenaline transporterMoclobemide Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126685Drug actionThere are 2 isoforms of this protein: A and B. The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … , norepinephrine, epinephrine, and dopamine.
Enzymes: Sodium-dependent noradrenaline transporterDuloxetine (SNRI) - Norepinephrine Reuptake Inhibiton
smpdb.ca/view/SMP0125000Drug actionIt blocks both sodium dependent serotonin and sodium dependent norepinephrine transporters from removing serotonin and norepinephrine respectively from the synaptic cleft. … The receptors that are being stimulated are 5-HT 2A, 2B, and 2C serotonin receptors and alpha 1 and beta 1 adrenergic receptors.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Norepinephrine · Duloxetine · Dopamine +4 moreEnzymes: Sodium-dependent noradrenaline transporterAtomoxetine Action Pathway (New)
smpdb.ca/view/SMP0126353Drug actionAtomoxetine binds to the sodium-dependent noradrenaline transporter, this prevents the noradrenaline reuptake in the presynaptic neurons. … Due to atomoxetine's noradrenergic activity, it also has effects on the cardiovascular system such as increased blood pressure and tachycardia.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Atomoxetine · Sapropterin · Norepinephrine +5 moreEnzymes: Sodium-dependent noradrenaline transporterCocaine Norepinephrine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126544Drug actionCocaine inhibits the sodium-dependent noradrenaline channel which causes norepinephrine to accumulate in the synapse. … It primarily acts on sensory neurons in the nasal cavity, but also inhibits dopamine, serotonin, and norepinephrine re-uptake channels.
Enzymes: Sodium-dependent noradrenaline transporter