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Aluminum zirconium tetrachlorohydrex gly
go.drugbank.com/drugs/DB11149ApprovedWithdrawnAluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Mixtures: Ban Ultra Antiperspirant Roll-ONProducts: Dove Invisible Antiperspirant, Dove Soft Solid AntiperspirantEpinephrine
go.drugbank.com/drugs/DB00668ApprovedInvestigationalVet approvedEpinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. … Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA.
Mixtures: Xylocaine 1.5% W Epinephrine 1:200000 Test Dose, Lidocaine Hydrochloride 1.5% and Epinephrine 1:200000 Injection USP Test DoseCategories: Sympathomimetics in Glaucoma Therapy, Adrenergic alpha-1 Receptor AgonistsIndium In-111 pentetate Drug Metabolism
smpdb.ca/view/SMP0130595MetabolicIndium In-111 pentetate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. … Indium In-111 pentetate passes through the liver and is then excreted from the body mainly through the kidney.
Drugs: Indium In-111 pentetatePyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalIn the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat dandruff and seborrheic dermatitis. … Pyrithione zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Mixtures: Z-plus Shampoo, Neutrogena T/Gel TherapeuticCategories: Heterocyclic Compounds, 1-RingNitric Oxide
go.drugbank.com/drugs/DB00435ApprovedInvestigationalThis gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. … It is also a toxic air pollutant produced by automobile engines and power plants.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: Stickstoff(II)-oxid, óxido de nitrógeno(II)Alfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D]. … The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback mechanism regulates the final activation step of vitamin D in the kidneys.
Categories: Vitamin D and AnaloguesSynonyms: 1-hydroxycholecalciferolGolimumab
go.drugbank.com/drugs/DB06674ApprovedInvestigationaltreatment in patients with active psoriatic arthritis (PsA), (iii) as a single agent in patients with active ankylosing spondylitis (AS), and (iv) as a single agent in patients with moderate to severe … Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate
Products: SIMPONI 100MG ILO IN FER, SIMPONI 50MG ILO IN FERTetracaine
go.drugbank.com/drugs/DB09085ApprovedInvestigationalVet approvedTetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Mixtures: Lidocaine 7% / Tetracaine 7%, Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%.Synonyms: 2-(dimethylamino)ethyl 4-(butylamino)benzoate, 2-(Dimethylamino)ethyl p-(butylamino)benzoateFc Epsilon Receptor I Signaling in Mast Cells
smpdb.ca/view/SMP0000358SignalingFc epsilon receptor 1 (Fc epsilon RI) is a high-affinity receptor for the Fc region of immunoglobulin E (IgE), an antibody isotope involved in allergies. … This activates the mast cells and results in degranulation, a process by which preformed granules containing histamine, proteoglycans, and serine proteases, are released.
Bazlitoran
go.drugbank.com/drugs/DB14990InvestigationalBazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Synonyms: DNA, D(P-THIO)(C-T-A-T-C-T-RGM-RUM-M5C-C7G-T-T-C-T-C-T-RGM-RUM), ALL-P-AMBO-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-O-METHYL-P-THIOGUANYLYL