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Displaying results 791 - 800 of 10000 in total
  1. Drug

    Potassium hydroxide

    go.drugbank.com/drugs/DB11153
    Approved

    [L1943] In addition to the above uses, potassium hydroxide is also used in making soap, as an electrolyte in alkaline batteries and in electroplating, lithography, and paint and varnish removers. … Potassium hydroxide, also known as _lye_ is an inorganic compound with the chemical formula _KOH_.

    Mixtures: Vamin N, NUTRIFLEX PERI IN 2000ML TWIN-FLEXCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Linaclotide

    go.drugbank.com/drugs/DB08890
    ApprovedInvestigational

    Linaclotide was first approved by the FDA on August 30, 2012.[A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013,[L47221] respectively. … Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C (G-CC) agonist.

  3. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    order to achieve blood pressure targets. … [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally.

    Mixtures: PERINDOPRIL E INDAPAMIDE EG, PERINDOPRIL E INDAPAMIDE EG
  4. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    an enzyme involved in the metabolism of many commonly used drugs. … clinical studies to result in a 45.8% to 54.6% decreases in LDL cholesterol levels, which is about three-fold more potent than [atorvastatin]'s effects on LDL cholesterol.

    Mixtures: ROSUVINA LEGRAND® E 10/40, ROSUVINA LEGRAND® E 10/20Categories: Drugs Used in Diabetes
  5. Drug

    Moxidectin

    go.drugbank.com/drugs/DB11431
    ApprovedInvestigationalVet approved

    It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of the milbemycin class. … [A33385] Moxidectin was developed by Medicines Development for Global Health and FDA approved in June 13, 2018.[L2970]

    Mixtures: Advocate Spot-on Solution for Small Dogs, Advocate Spot-on Solution for Large DogsCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Hydralazine

    go.drugbank.com/drugs/DB01275
    ApprovedInvestigational

    [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure. … [T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779]

    Mixtures: Ser-Ap-Es, Ser-AP-ES TabCategories: Arteriolar Smooth Muscle, Agents Acting On
  7. Drug

    Naltrexone

    go.drugbank.com/drugs/DB00704
    ApprovedInvestigationalVet approved

    Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone.

    Mixtures: Troxyca ER, Troxyca ERCategories: Drugs Used in Alcohol Dependence, Drugs Used in Addictive Disorders
  8. Drug

    Ethinylestradiol

    go.drugbank.com/drugs/DB00977
    ApprovedInvestigational

    Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability. … [A191107] These properties were achieved by the substitution of an ethinyl group at carbon 17 of [estradiol].[A191107] Ethinylestradiol soon replaced [mestranol] in contraceptive pills.

    Mixtures: Lenea 20 µg/75 µg überzogene Tabletten, Aubra EQProducts: ETINILESTRADIOLO E DROSPIRENONE DOC, LEVONORGESTREL E ETINILESTRADIOLO AUROBINDO
  9. Drug

    Sodium hydroxide

    go.drugbank.com/drugs/DB11151
    Approved

    The use of this compound has been shown to effectively reduce prion levels in an in vitro inactivation assay [A32334]. … Interestingly, sodium hydroxide has been studied for its use in the treatment of prion disease (as occurs in mad cow disease and kuru).

    Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% ECategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Ergocalciferol

    go.drugbank.com/drugs/DB00153
    ApprovedInvestigationalNutraceutical

    Ergocalciferol is an inactivated vitamin D analog.[A177526] It is synthesized by some plants in the presence of UVB light. … Ergocalciferol was isolated for the first time from yeast in 1931 and its structure was elucidated in 1932.

    Mixtures: Formula EC, Vitamines Pour Bebes Et Enfants