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Displaying results 801 - 810 of 10000 in total
  1. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001907
    TargetRSV-SRA

    Capsid protein p27: Self-associates to form the irregular polyhedron core composed of hexamers and pentamers, that encapsulates the genomic RNA-nucleocapsid complex. Assembles as a tube in vitro. Binds to inositol hexakisphosphate (IP6),...

    Polypeptides: Gag-Pol polyproteinSynonyms: Gag-Pro-Pol polyprotein
  2. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0004120
    Target

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  3. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site.

    Categories: Antibiotics for Topical Use, Antibacterials for Systemic UseProducts: PIPERACILLINA E TAZOBACTAM EG, Tetracycline 3 percent a First Aid Antibiotic
  4. Drug

    Leucine

    go.drugbank.com/drugs/DB00149
    ApprovedInvestigationalNutraceutical

    An essential branched-chain amino acid important for hemoglobin formation.

    Salts: L-Leucine hydrochlorideMixtures: Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec, Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
  5. Drug

    Fusidic acid

    go.drugbank.com/drugs/DB02703
    ApprovedInvestigational

    An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. … It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.

    Mixtures: M-FURO FA %0.1 + %2 KREM, 30 GCategories: Antibiotics for Topical Use, Antibacterials for Systemic Use
  6. Drug

    Voriconazole

    go.drugbank.com/drugs/DB00582
    ApprovedInvestigational

    Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. … The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [fluconazole]-resistant organisms.

    Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: VORICONAZOLO EG, VORICONAZOLO EG STADA
  7. Drug

    Bromhexine

    go.drugbank.com/drugs/DB09019
    ApprovedInvestigational

    Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.

    Synonyms: N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamineMixtures: PENBRITIN EX, GLICERTOX N F
  8. Drug

    alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14003
    Approved

    Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement. … This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number

    Mixtures: DIO Enamel Coating Pen Pro Tooth, DIO Enamel Coating Pen Pro ToothCategories: Compounds used in a research, industrial, or household setting, Vitamin E
  9. Drug

    Potassium Iodide

    go.drugbank.com/drugs/DB06715
    ApprovedInvestigational

    SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy. … Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperthyroidism (also known as thyroid storm or thyrotoxic crisis

    Mixtures: ADDAMEL N FOR INFUSION, Multivitamins and Minerals for Men
  10. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common and effective treatment for erectile dysfunction and since its formal approval for medical use in … Interestingly enough, it is precisely via this mechanism why sildenafil was at first researched as a potential treatment for angina - or chest pain associated with inadequate blood flow to the heart -

    Categories: Drugs Used in Erectile DysfunctionProducts: SILDENAFIL EG, SILDENAFIL EG STADA ITALIA