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Displaying results 801 - 810 of 10000 in total
  1. Target

    Excretory Secretory (ES) proteins

    go.drugbank.com/bio_entities/BE0009630
    TargetFasciola hepatica

    Synonyms: Glutathione S-transferase omega classPolypeptides: Glutathione S-transferase omega class
  2. Target

    Laminin subunit gamma-1

    go.drugbank.com/bio_entities/BE0002107
    TargetHumans

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. As a su...

    Synonyms: S-LAM gamma, S-laminin subunit gamma
  3. Target

    Kynurenine--oxoglutarate transaminase 3

    go.drugbank.com/bio_entities/BE0002162
    TargetHumans

    May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.

    Synonyms: Cysteine-S-conjugate beta-lyase 2Function: cysteine-S-conjugate beta-lyase activity
  4. Target

    Nitric oxide synthase 1

    go.drugbank.com/bio_entities/BE0000067
    TargetEnzymeHumans

    Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR

    Synonyms: Peptidyl-cysteine S-nitrosylase NOS1
  5. Target

    4-aminobutyrate aminotransferase, mitochondrial

    go.drugbank.com/bio_entities/BE0000253
    TargetEnzymeHumans

    Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively (PubMed:10407778, PubMed:15528998). Can also convert delta-aminovalerate and beta-alanine...

    Synonyms: (S)-3-amino-2-methylpropionate transaminaseFunction: (S)-3-amino-2-methylpropionate
  6. Target

    Cyclopropane mycolic acid synthase MmaA2

    go.drugbank.com/bio_entities/BE0002512
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  7. Drug

    Netarsudil

    go.drugbank.com/drugs/DB13931
    ApprovedInvestigational

    solution) 0.02% for the indication of reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. … Acting as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel glaucoma medication in that it specifically targets the conventional trabecular pathway of aqueous

    Synonyms: (4-((1S)-1-(Aminomethyl)-2-(isoquinolin-6-ylamino)-2-oxoethyl)phenyl)methyl 2,4- dimethylbenzoate
  8. Target

    Putative hydrolase DDAH2

    go.drugbank.com/bio_entities/BE0000608
    TargetHumans

    Putative hydrolase with unknown substrate (Probable). Does not hydrolyze N(G),N(G)-dimethyl-L-arginine (ADMA) which acts as an inhibitor of NOS (PubMed:21493890, PubMed:37296100). In endothelial cells, induces expression of vascular endo...

    Synonyms: S-phase protein
  9. Target

    Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

    go.drugbank.com/bio_entities/BE0002256
    TargetEnzymeHumans

    Key enzyme for ketone body catabolism. Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate...

    Synonyms: SCOT-s
  10. Drug

    Benzocaine

    go.drugbank.com/drugs/DB01086
    ApprovedInvestigational

    Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. … [A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259]

    Synonyms: p-Carbethoxyaniline, Ethyl p-aminobenzoateMixtures: Coghlan s Sting Relief, Adventure Medical Kits 1-4 Person First Aid