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Ethoxzolamide
go.drugbank.com/drugs/DB00311ApprovedWithdrawnEthoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 6-Ethoxy-1,3-benzothiazole-2-sulfonamideValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigational[A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … a similar degree of anticonvulsive activity.
Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSynonyms: 2-n-propyl-n-valeric acid, n-DPAZolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigationalZolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine. … [A193797] Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the trade name Zomig® on November 25, 1997.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one, 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-oneAcetaminophen
go.drugbank.com/drugs/DB00316ApprovedInvestigationalFDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent tablets, injection, suppository, and other forms. … the Society of Obstetricians and Gynaecologists of Canada (SOGC)[L53931] and the American College of Obstetricians and Gynecologists (ACOG)[L53936]- maintain that acetaminophen use in pregnancy remains a
Synonyms: N-acetyl-p-aminophenol, 4-acetamidophenolInternational brands: Dapa X-S, Anacin-3Codeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalThe relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.
Mixtures: Fiorinal-C 1/4, Fiorinal-C 1/2Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAmitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961.
Mixtures: โพลีบอน 4-10, Etrafon 2 10Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders.
Mixtures: FLU-SURE T® SUSPENSIÓN OFTÁLMICA, FML-SCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersNitrofural
go.drugbank.com/drugs/DB00336ApprovedVet approvedWithdrawnNitrofural or nitrofurazone is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections.
Mixtures: MADECASSOL CCategories: Heterocyclic Compounds, 1-RingMetixene
go.drugbank.com/drugs/DB00340ApprovedMetixene (or methixene) is a anticholinergic used as an antiparkinsonian agent.
Categories: Heterocyclic Compounds, 3-Ring, Serotonin 5-HT2 Receptor AntagonistsTerfenadine
go.drugbank.com/drugs/DB00342ApprovedWithdrawnIn the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol