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Displaying results 831 - 840 of 10000 in total
  1. Target

    Acyl-coenzyme A thioesterase 1

    go.drugbank.com/bio_entities/BE0016368
    EnzymeHumans

    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels.

    Polypeptides: Acyl-coenzyme A thioesterase 1Synonyms: Palmitoyl-coenzyme A thioesterase, Inducible cytosolic acyl-coenzyme A thioester hydrolase
  2. Indication

    Perioperative Bleeding caused by Hemophilia A

    go.drugbank.com/conditions/DBCOND0089513
    Drugs: Anti-inhibitor coagulant complex
    Synonyms: Perioperative Bleeding caused by Hemophilia A
  3. Drug

    Aztreonam

    go.drugbank.com/drugs/DB00355
    ApprovedInvestigational

    It may cause a superinfection with gram-positive organisms. … A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid, 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid
  4. Indication

    Symptomatic Botulism caused by Clostridium botulinum serotype A

    go.drugbank.com/conditions/DBCOND0093883
    Drugs: Equine Botulinum Neurotoxin A Immune FAB2
    Synonyms: Symptomatic Botulism caused by Clostridium botulinum serotype A
  5. Drug

    Potassium

    go.drugbank.com/drugs/DB14500
    ApprovedInvestigational

    Potassium is an essential nutrient, like [Calcium] and [Magnesium]. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. … Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for rehydration, nutrition, and replenishment of electrolytes.

    Mixtures: One A Day Tab, One A Day Multiple Vit W MineralsSynonyms: K
  6. Drug

    Aluminum zirconium tetrachlorohydrex gly

    go.drugbank.com/drugs/DB11149
    ApprovedWithdrawn

    Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent.

    Products: Ban U. Fr. & Dry Wo Ap Roll-ON W Aloe-skiing, Lady Speed Stick Antipers 22% Frag Free
  7. Target

    GABA(A) Receptor Benzodiazepine Binding Site

    go.drugbank.com/bio_entities/BE0008668
    TargetHumans

    GABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response in a gamma-2 subunit-controlled manner (By similarity) … GABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response (By similarity).

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-2Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2
  8. Target

    Hepatitis A virus cellular receptor 2

    go.drugbank.com/bio_entities/BE0010551
    TargetHumans

    Expressed on natural killer (NK) cells and acts as a coreceptor to enhance IFN-gamma production in response to LGALS9 (PubMed:22323453). … Receptor for LGALS9 (PubMed:16286920, PubMed:24337741).

    Polypeptides: Hepatitis A virus cellular receptor 2Synonyms: T-cell immunoglobulin mucin receptor 3
  9. Drug

    Plasma protein fraction (human)

    go.drugbank.com/drugs/DB13968
    ApprovedInvestigational

    The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. … It is also stated that no more than 1% of the total protein should be gamma globulin.[L2260] PPFh is a sterile, frozen solution of solvent/detergent treated human plasma.

    Products: OCTAPLAS Blood Group A, Octaplas SD Blutgruppe A zur Infusion
  10. Drug

    Insulin glargine

    go.drugbank.com/drugs/DB00047
    ApprovedInvestigational

    In 2021, another biosimilar, Semglee (insulin glargine-yfgn),[L34959] became the first interchangeable (with Lantus) biosimilar insulin to receive FDA approval. … If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening

    Mixtures: Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen, Soliqua SoloStar 100units/mL+50mcg/mL solution for injection in a pre-filled penCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers