GABA(A) Receptor Benzodiazepine Binding Site

BE0008668Protein groupHumans

GABA(A) receptors are pentameric receptors, meaning each receptor isoform is comprised of 5 subunits. It is acted on by 48 drugs in DrugBank.

Proteins: Gamma-aminobutyric acid receptor subunit alpha-1
Gamma-aminobutyric acid receptor subunit alpha-2
Gamma-aminobutyric acid receptor subunit alpha-3
Gamma-aminobutyric acid receptor subunit alpha-5
Gamma-aminobutyric acid receptor subunit gamma-1
Gamma-aminobutyric acid receptor subunit gamma-2
Gamma-aminobutyric acid receptor subunit gamma-3

What you can answer from here — as of May 05, 2020

48DrugsApproved to experimental, with action, bond type and pharmacological action

93+ReferencesStructured and connected to the statements they support

Which approved drugs act on GABA(A) Receptor Benzodiazepine Binding Site, how selective are they, and which programs against it are still in active trials?

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