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Marimastat
go.drugbank.com/drugs/DB00786InvestigationalUsed in the treatment of cancer, Marmiastat is an angiogenesis and metastasis inhibitor. As an angiogenesis inhibitor it limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from brea...
Naproxen
go.drugbank.com/drugs/DB00788ApprovedInvestigationalVet approved[A179098] Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia. … [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile.
Synonyms: (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, (S)-2-(6-Methoxy-2-naphthyl)propanoic acidInternational brands: Bumaflex N, Proxen SPerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalPerindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).
Synonyms: (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acidMixtures: ./5 มก./5 มก., COSYREL 5/5Uracil mustard
go.drugbank.com/drugs/DB00791ApprovedIt is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.
Synonyms: 5-N,N-bis(2-chloroethyl)aminouracil, 5-(di-2-chloroethyl)aminouracilCategories: Heterocyclic Compounds, 1-RingCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalCandesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents
Mixtures: CANDAM ® H 5/32/12.5, CANDAM® H 5/16/12.5 MGCategories: Angiotensin 2 Receptor Blocker, P-glycoprotein inhibitorsTolazoline
go.drugbank.com/drugs/DB00797ApprovedVet approvedWithdrawnA vasodilator that apparently has direct actions on blood vessels and also increases cardiac output.
Synonyms: 2-Benzyl-2-imidazoline, 2-BenzylimidazolineCategories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approvedGentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity
International brands: G-Mycin, U-gencinMixtures: TROK G® CREMA, B-TASONE-G CREAMFenoldopam
go.drugbank.com/drugs/DB00800ApprovedA dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Categories: Heterocyclic Compounds, 2-RingAlfentanil
go.drugbank.com/drugs/DB00802ApprovedIllicitInvestigationalA short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness.
Synonyms: N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilideCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesColistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalIt is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. … Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Synonyms: Polymyxin EMixtures: Coly-Mycin S, Coly-Mycin S