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Displaying results 8481 - 8490 of 10000 in total
  1. Drug

    Diamorphine

    go.drugbank.com/drugs/DB01452
    ApprovedIllicit

    Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. … Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S.

    Categories: Heterocyclic Compounds with 4 or More RingsSynonyms: O,O'-Diacetylmorphine
  2. Pathway

    Acylcarnitine (2E)-4-Hydroxytetradec-2-enoylcarnitine

    smpdb.ca/view/SMP0124157
    Metabolic

    (2E)-4-Hydroxytetradec-2-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2E)-4-hydroxytetradec-2-enoyl-CoA reacts with L-carnitine to form (2E)-4-hydroxytetradec-2-enoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  3. Drug

    Cinpanemab

    go.drugbank.com/drugs/DB16127
    Investigational

    Cinpanemab is under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease).

    Synonyms: Immunoglobulin g1-lambda, anti-(homo sapiens alpha-synuclein)humanized monoclonal antibody.gamma.1 heavy chain (1-442) (homo sapiens vh (ighv3-25*03 (86%) (ighd)-ighj2*01) (8.10.4) (1-113)-homo sapiens, Immunoglobulin g1-lambda, anti-(homo sapiens snca (synuclein alpha, alpha-synuclein, park1, park4, parkinson disease (autosomal dominant, lewy body) 4, non a4 component of amyloid precursor, nacp)), monoclonal
  4. Drug

    Misoprostol

    go.drugbank.com/drugs/DB00929
    ApprovedInvestigational

    Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. … [A181586] Misoprostol was granted FDA approval on 27 December 1988.[L7616]

    Mixtures: DIFEMIS 50 MG/0.2 MG TABLET, 30 ADET, DIFEMIS 75 MG/0.2 MG TABLET, 30 ADETCategories: Prostaglandins E, Synthetic
  5. Pathway

    Acylcarnitine (4E)-2-Hydroxyundec-4-enoylcarnitine

    smpdb.ca/view/SMP0123961
    Metabolic

    (4E)-2-Hydroxyundec-4-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (4E)-2-hydroxyundec-4-enoyl-CoA reacts with L-carnitine to form (4E)-2-hydroxyundec-4-enoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  6. Target

    Peroxiredoxin-2

    go.drugbank.com/bio_entities/BE0001972
    TargetHumans

    Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)

    Polypeptides: Peroxiredoxin-2Synonyms: Thioredoxin-dependent peroxiredoxin 2
  7. Target

    Synaptotagmin-2

    go.drugbank.com/bio_entities/BE0002138
    TargetHumans

    Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By ...

    Polypeptides: Synaptotagmin-2
  8. Target

    Stromelysin-2

    go.drugbank.com/bio_entities/BE0003689
    TargetHumans

    Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase

    Polypeptides: Stromelysin-2Synonyms: SL-2, Transin-2
  9. Target

    Profilin-2

    go.drugbank.com/bio_entities/BE0004295
    TargetHumans

    Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG

    Polypeptides: Profilin-2
  10. Target

    Nucleobindin-2

    go.drugbank.com/bio_entities/BE0008701
    TargetHumans

    Calcium-binding protein which may have a role in calcium homeostasis (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G protein) alpha subunit GNA...

    Polypeptides: Nucleobindin-2